DHPS Antikörper

Produktnummer ABIN499058

Produktdetails anti-DHPS Antikörper

Target: DHPS (Deoxyhypusine Synthase (DHPS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of DHS protein. (region surrounding Leu87)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DHPS

Target: DHPS (Deoxyhypusine Synthase (DHPS))

Abstract: DHPS Produkte

Synonyme: MGC76269 antikoerper, zgc:56018 antikoerper, zgc:77325 antikoerper, wu:fb52g04 antikoerper, wu:fj48f12 antikoerper, zgc:111900 antikoerper, MGC82178 antikoerper, DDBDRAFT_0186679 antikoerper, DDBDRAFT_0266388 antikoerper, DDB_0186679 antikoerper, DDB_0266388 antikoerper, DHS antikoerper, DS antikoerper, MIG13 antikoerper, Dhs antikoerper, DYS antikoerper, EDA22 antikoerper, K18J17.7 antikoerper, K18J17_7 antikoerper, deoxyhypusine synthase antikoerper, embryo sac development arrest 22 antikoerper, deoxyhypusine synthase antikoerper, deoxyhypusine synthase S homeolog antikoerper, Deoxyhypusine synthase antikoerper, DHPS antikoerper, dhps antikoerper, dhps.S antikoerper, SHELL_RS05250 antikoerper, PF14_0125 antikoerper, CNJ02480 antikoerper, Tb10.70.4900 antikoerper, Tb927.1.870 antikoerper, MMAH_RS09430 antikoerper, TAGG_RS03310 antikoerper, TAGG_RS05175 antikoerper, Mesil_2448 antikoerper, Trad_0088 antikoerper, Igag_1842 antikoerper, Desac_0724 antikoerper, MZHIL_RS05480 antikoerper, MZHIL_RS05835 antikoerper, MZHIL_RS06250 antikoerper, Dhps antikoerper, DHS antikoerper

Hintergrund: Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.

Molekulargewicht: approx. 45 kDa

Gen-ID: 1725

NCBI Accession: NP_001921

UniProt: P49366