ACVR2A Antikörper

Produktnummer ABIN498661

Produktdetails anti-ACVR2A Antikörper

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of ACTRIIA protein. (region surrounding His59)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-ACVR2A Antikörper (ABIN498661)

Reichel, Farmer, Gmeiner, Walpurgis, Thevis: "Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." in: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).

Details zu ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Andere Bezeichnung: Activin Receptor Type 2A (ACVR2A) (ACVR2A Produkte)

Synonyme: ACVR2 antikoerper, ACVR2A antikoerper, XSTK9 antikoerper, actrii antikoerper, acvr2 antikoerper, ACTRII antikoerper, Acvr2 antikoerper, rActR-II antikoerper, actr2a antikoerper, acvr2a antikoerper, wu:fa02e10 antikoerper, ActrIIa antikoerper, TactrII antikoerper, activin A receptor type 2A antikoerper, activin A receptor type 2A L homeolog antikoerper, activin A receptor type 2Aa antikoerper, activin receptor IIA antikoerper, ACVR2A antikoerper, acvr2a antikoerper, Acvr2a antikoerper, acvr2a.L antikoerper, acvr2aa antikoerper

Hintergrund: Members of the transforming growth factor beta superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTRIIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.Synonyms: ACTR-IIA, ACTRIIA, Activin A receptor type IIA

Molekulargewicht: approx. 48 kDa

Gen-ID: 92

NCBI Accession: NP_001607

UniProt: P27037