RBPJ Antikörper (AA 1-29)

Produktnummer ABIN3032451

Dieses Anti-RBPJ-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RBPJ in WB, ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für RBPJ Antikörper (AA 1-29) (ABIN3032451)

Target: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBPJ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RBPJ Antikörper

Bindungsspezifität: AA 1-29

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RBPJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-2000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RBPJ antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RBPJ

Target: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Andere Bezeichnung: RBPJ

Hintergrund: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

UniProt: Q06330

Pathways: Notch Signalweg, Stem Cell Maintenance, Smooth Muscle Cell Migration