IL1R1 Antikörper (AA 422-450)

Produktnummer ABIN3031430

Produktdetails anti-IL1R1 Antikörper

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Bindungsspezifität: AA 422-450

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1R1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 422-450 from the human protein was used as the immunogen for this IL1R1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the IL1R1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IL1R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu IL1R1

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Andere Bezeichnung: IL-1 Receptor type 1 (IL1R1 Produkte)

Synonyme: CD121A antikoerper, D2S1473 antikoerper, IL-1R-alpha antikoerper, IL1R antikoerper, IL1RA antikoerper, P80 antikoerper, CD121a antikoerper, CD121b antikoerper, IL-iR antikoerper, Il1r-1 antikoerper, DER4 antikoerper, Fit-1 antikoerper, Ly84 antikoerper, ST2L antikoerper, St2 antikoerper, St2-rs1 antikoerper, T1 antikoerper, T1/ST2 antikoerper, interleukin 1 receptor type 1 antikoerper, interleukin 1 receptor, type I antikoerper, interleukin 1 receptor-like 1 antikoerper, IL1R1 antikoerper, Il1r1 antikoerper, Il1rl1 antikoerper

Hintergrund: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

UniProt: P14778

Pathways: NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints