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PRKAA1 Antikörper (AA 479-510)
PRKAA1
Reaktivität: Human, Maus
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN3032383
Produktdetails anti-PRKAA1 Antikörper
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Target
Alle PRKAA1 Antikörper anzeigen
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Bindungsspezifität
Alle Epitope für PRKAA1 Antikörper
AA 479-510
Reaktivität
Alle Reaktivitäten für PRKAA1 Antikörper
Human, Maus
Wirt
Alle Wirte für PRKAA1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PRKAA1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PRKAA1 Antikörper
Dieser PRKAA1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PRKAA1 Antikörper
Western Blotting (WB), ELISA
Aufreinigung
Purified
Immunogen
A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody.
Isotyp
Ig Fraction
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Discover our top product PRKAA1 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the AMPK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Details zu PRKAA1
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Target
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Andere Bezeichnung
AMPK (PRKAA1) (PRKAA1 Produkte )
Synonyme
AMPK antikoerper, AMPKa1 antikoerper, cb116 antikoerper, im:7154392 antikoerper, sb:cb130 antikoerper, wu:fa94c10 antikoerper, AMPK1 antikoerper, AMPKalpha1 antikoerper, AI194361 antikoerper, AI450832 antikoerper, AL024255 antikoerper, C130083N04Rik antikoerper, ampk antikoerper, ampka1 antikoerper, PRKAA1 antikoerper, protein kinase AMP-activated catalytic subunit alpha 1 antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antikoerper, PRKAA1 antikoerper, prkaa1 antikoerper, Prkaa1 antikoerper, prkaa1.L antikoerper
Hintergrund
AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
UniProt
Q13131
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effekt
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