Nestin Antikörper
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- Target Alle Nestin (NES) Antikörper anzeigen
- Nestin (NES)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Nestin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Aufreinigung
- Antigen affinity
- Immunogen
- Amino acids ERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAH of human NES were used as the immunogen for the Nestin antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product NES Primärantikörper
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- Applikationshinweise
- Optimal dilution of the Nestin antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the Nestin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Nestin (NES)
- Andere Bezeichnung
- Nestin (NES Produkte)
- Synonyme
- paranemin antikoerper, NES antikoerper, AA166324 antikoerper, C78523 antikoerper, ESTM46 antikoerper, nestin antikoerper, nestin S homeolog antikoerper, NES antikoerper, nes.S antikoerper, Nes antikoerper, nes antikoerper
- Hintergrund
- Nestin is a type VI intermediate filament (IF) protein that in humans is encoded by the NES gene. Distribution and expression of nestin in mitotically active cells suggests it plays a role in regulation of the assembly and disassembly of intermediate filaments, which, together with other structural proteins, participate in remodeling of the cell. The role of nestin in dynamic cells, particularly structural organization of the cell, appears strictly regulated by phosphorylation, especially its integration into heterogeneous intermediate filaments together with vimentin or α,-internexin. Furthermore, nestin expression has been extensively used as a marker for central nervous system (CNS) progenitor cells in different contexts, based on observations indicating a correlation between nestin expression and this cell type in vivo.
- UniProt
- P48681
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