MGP Antikörper

Produktnummer ABIN4951722

Produktdetails anti-MGP Antikörper

Target: MGP (Matrix Gla Protein (MGP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MGP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids Y20-F96 from the human protein were used as the immunogen for the MGP antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MGP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MGP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu MGP

Target: MGP (Matrix Gla Protein (MGP))

Andere Bezeichnung: MGP / Matrix Gla protein (MGP Produkte)

Synonyme: MGLAP antikoerper, NTI antikoerper, Mglap antikoerper, mgp-A antikoerper, MGP antikoerper, LOC100136434 antikoerper, mgp antikoerper, matrix Gla protein antikoerper, matrix Gla protein L homeolog antikoerper, MGP antikoerper, Mgp antikoerper, mgp.L antikoerper, mgp antikoerper

Hintergrund: Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. In addition, MGP is a 10-kD protein produced and secreted by vascular smooth muscle cells and chondrocytes and significantly accumulated in bone, cartilage, and dentin. It is also expressed at high levels in heart, kidney, and lung and is upregulated by vitamin D in bone cells. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. And this gene is mapped to 12p12.3.

UniProt: P08493