HINT1 Antikörper
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- Target Alle HINT1 Antikörper anzeigen
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HINT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Antigen affinity
- Immunogen
- Amino acids HISQISVAEDDDESLLGHLMIVGKKCAADLGLNK of human HINT1 were used as the immunogen for the HINT1 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product HINT1 Primärantikörper
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- Applikationshinweise
- Optimal dilution of the HINT1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the HINT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Andere Bezeichnung
- HINT1 (HINT1 Produkte)
- Synonyme
- hint antikoerper, pkci-1 antikoerper, prkcnh1 antikoerper, HINT antikoerper, NMAN antikoerper, PKCI-1 antikoerper, PRKCNH1 antikoerper, AA673479 antikoerper, Hint antikoerper, Ipk1 antikoerper, Pkci antikoerper, Prkci antikoerper, zgc:103764 antikoerper, CHPKCI antikoerper, HINTZ antikoerper, PKCIZ antikoerper, histidine triad nucleotide binding protein 1 antikoerper, histidine triad nucleotide binding protein 1 S homeolog antikoerper, histidine triad nucleotide binding protein 1-Z antikoerper, Histidine triad nucleotide-binding protein 1 antikoerper, HINT1 antikoerper, hint1 antikoerper, Hint1 antikoerper, hint1.S antikoerper, HINT1Z antikoerper, hint-1 antikoerper
- Hintergrund
- Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene. It is a haploinsufficient tumor suppressor gene that inhibits the Wnt/b-catenin pathway in colon cancer cells and Microphthalmia-associated transcription factor (MITF) activity in human mast cells. The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. Several transcript variants, but only one of them protein-coding, have been found for this gene.
- UniProt
- P49773
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