KAT2A Antikörper

Produktnummer ABIN4951155

Produktdetails anti-KAT2A Antikörper

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids DPARPGLSQQQRASQRKAQVRGLPRAKKLEKL of human KAT2A/GCN5 were used as the immunogen for the GCN5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GCN5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the GCN5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Andere Bezeichnung: GCN5 / KAT2A (KAT2A Produkte)

Synonyme: KAT2A antikoerper, GCN5L2 antikoerper, GCN5 antikoerper, PCAF-b antikoerper, hGCN5 antikoerper, 1110051E14Rik antikoerper, AW212720 antikoerper, Gcn5 antikoerper, Gcn5l2 antikoerper, mmGCN5 antikoerper, K(lysine) acetyltransferase 2A antikoerper, lysine acetyltransferase 2A antikoerper, histone acetyltransferase KAT2A antikoerper, ras-related protein Rab-5C antikoerper, KAT2A antikoerper, LOC100176452 antikoerper, LOC100597293 antikoerper, Kat2a antikoerper

Hintergrund: Histone acetyltransferase KAT2A, also called GCN5 and GCN5L2, is an enzyme that in humans is encoded by the KAT2A gene. It is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex. The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation