CHD4 Antikörper (Chromodomain Helicase DNA Binding Protein 4) (AA 1632-1731)

Details for Product anti-CHD4 Antibody No. ABIN4948202, Anbieter: Anmelden zum Anzeigen
Antigen
  • CHD4
  • im:7143343
  • si:ch211-51m24.3
  • si:ch211-57k11.10
  • wu:fb44b12
  • wu:fd12d03
  • MGC145363
  • Mi-2b
  • Mi2-BETA
  • Mi-2
  • 9530019N15Rik
  • AA617397
  • BC005710
  • D6Ertd380e
  • Mi-2beta
  • mKIAA4075
  • b230399n07
  • chromodomain helicase DNA binding protein 4
  • chromodomain helicase DNA binding protein 4a
  • chromodomain helicase DNA binding protein 4b
  • chromodomain helicase DNA binding protein 4 L homeolog
  • CHD4
  • chd4a
  • chd4b
  • chd4
  • Chd4
  • chd4.L
Epitop
AA 1632-1731
5
4
4
4
3
2
2
2
2
2
1
1
1
1
1
Reaktivität
Human
84
53
11
4
4
4
4
4
4
2
1
1
1
1
1
Wirt
Maus
45
42
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser CHD4 Antikörper ist unkonjugiert
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
63
47
43
21
19
17
9
7
7
3
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen CHD4 (NP_001264, 1632 a.a. ~ 1731 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Klon 4H4
Isotyp IgG2a kappa
Spezifität CHD4 (NP_001264, 1632 a.a. ~ 1731 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Reinigung Purified
Plasmids, Primers & others Plasmide, Primers & weitere CHD4 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CHD4 (CHD4 Antibody Abstract)
Hintergrund The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.
Synonyms: Mi2b, Mi2BETA chromodomain helicase DNA binding protein 4
Molekulargewicht 217991 DA
Gen-ID 1108
NCBI Accession NP_001264
Applikations-hinweise Western blot = 1:500-1000
Kommentare

Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer Phosphate buffered saline, pH 7.2
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody (ABIN4948202) anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody
Western Blotting (WB) image for anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody (ABIN4948202) Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunoge...
Western Blotting (WB) image for anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody (ABIN4948202) CHD4 monoclonal antibody (M01), clone 4H4 Western Blot analysis of CHD4 expression in...
Western Blotting (WB) image for anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody (ABIN4948202) Western Blot analysis of CHD4 expression in transfected 293T cell line by CHD4 monocl...
Immunohistochemistry (IHC) image for anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody (ABIN4948202) Immunoperoxidase of monoclonal antibody to CHD4 on formalin-fixed paraffin-embedded h...
ELISA image for anti-Chromodomain Helicase DNA Binding Protein 4 (CHD4) (AA 1632-1731) antibody (ABIN4948202) Detection limit for recombinant GST tagged CHD4 is approximately 0.03ng/ml as a captu...
Allgemeine Veröffentlichungen Li, Zhang, Yu, Chen, Gui, Liang, Wang, Sun, Yang, Zhang, Shi, Li, Shang: "ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis." in: The EMBO journal, Vol. 28, Issue 18, pp. 2763-76, 2009 (PubMed).

Musselman, Mansfield, Garske, Davrazou, Kwan, Oliver, OLeary, Denu, Mackay, Kutateladze: "Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications." in: The Biochemical journal, Vol. 423, Issue 2, pp. 179-87, 2009 (PubMed).

Sowa, Bennett, Gygi, Harper: "Defining the human deubiquitinating enzyme interaction landscape." in: Cell, Vol. 138, Issue 2, pp. 389-403, 2009 (PubMed).

Helbling Chadwick, Chadwick, Jaye, Wade: "The Mi-2/NuRD complex associates with pericentromeric heterochromatin during S phase in rapidly proliferating lymphoid cells." in: Chromosoma, Vol. 118, Issue 4, pp. 445-57, 2009 (PubMed).

Ishii, Du, Zhang, Henderson, Sen, Pazin: "Mi2beta shows chromatin enzyme specificity by erasing a DNase I-hypersensitive site established by ACF." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7533-41, 2009 (PubMed).

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