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GNE Antikörper

GNE Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4903788
  • Target Alle GNE Antikörper anzeigen
    GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 53
    • 1
    Kaninchen
    Klonalität
    • 53
    • 1
    Polyklonal
    Konjugat
    • 20
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GNE Antikörper ist unkonjugiert
    Applikation
    • 53
    • 29
    • 19
    • 13
    • 13
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human GNE.
    Isotyp
    IgG
    Top Product
    Discover our top product GNE Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 , IHC 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C.
  • Target
    GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
    Andere Bezeichnung
    GNE (GNE Produkte)
    Synonyme
    DMRV antikoerper, GLCNE antikoerper, IBM2 antikoerper, UAE1 antikoerper, zgc:77657 antikoerper, GNE antikoerper, MGC145505 antikoerper, NM antikoerper, Uae1 antikoerper, 2310066H07Rik antikoerper, glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase antikoerper, GNE antikoerper, gne antikoerper, Gne antikoerper
    Gen-ID
    10020
    UniProt
    Q9Y223
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