Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2) Antikörper

Details zu Produkt Nr. ABIN4900831, Anbieter: Anmelden zum Anzeigen
Antigen
  • CD159c
  • NKG2-C
  • NKG2C
  • killer cell lectin like receptor C2
  • killer cell lectin-like receptor subfamily C, member 2
  • KLRC2
Reaktivität
Human
72
8
Wirt
Maus
40
40
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
5
4
4
4
4
4
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
49
30
19
5
3
2
2
2
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
Klon 134522
Isotyp IgG2b
Spezifität Detects human NKG2C/CD159c. Detects human NKG2C/CD159c as part of the NKG2C/CD94 heterodimer in flow cytometry. No cross-reactivity with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer is detected.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.10 EU per 1 μg of the antibody by the LAL method.
Antigen
Andere Bezeichnung NKG2C/CD159c (KLRC2 Antibody Abstract)
Hintergrund Alternative Names: CD159 antigen-like family member C, CD159c, CD159c antigen, killer cell lectin-like receptor subfamily C, member 2, KLRC2, MGC138244, NK cell receptor C, NKG2-C, NKG2-C type II integral membrane protein, NKG2CNKG2-C-activating NK receptor
Gen-ID 3822
Applikations-hinweise Flow Cytometry 0.25 μg/10^6 cells
CyTOF-reported
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungs-mittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2) antibody (ABIN4900831) Detection of NKG2C/CD159c in Human Blood Lymphocytes by Flow Cytometry. Human periphe...
Produkt verwendet in: Horowitz, Guethlein, Nemat-Gorgani, Norman, Cooley, Miller, Parham: "Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 9, pp. 4524-36, 2015 (PubMed). Von den Autoren verwendete Methode: Mass Cytometry (CyTOF) (Probematerial (Species): Human).

Anton, Vielkind, Peterson, Tagaya, Long: "NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 10, pp. 4810-21, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Costa-Garcia, Vera, Moraru, Vilches, López-Botet, Muntasell: "Antibody-mediated response of NKG2Cbright NK cells against human cytomegalovirus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 6, pp. 2715-24, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Alici, Sutlu, Björkstrand, Gilljam, Stellan, Nahi, Quezada, Gahrton, Ljunggren, Dilber: "Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components." in: Blood, Vol. 111, Issue 6, pp. 3155-62, 2008 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Coupel, Moreau, Hamidou, Horejsi, Soulillou, Charreau: "Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation." in: Blood, Vol. 109, Issue 7, pp. 2806-14, 2007 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

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