Applikations-hinweise |
Flow Cytometry 0.25 μg/10^6 cells Immunohistochemistry 8-25 μg/mL CyTOF-ready |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
Rekonstitution | Reconstitute at 0.5 mg/mL in sterile PBS. |
Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
Konservierungs-mittel | Without preservative |
Lagerung | 4 °C,-20 °C,-80 °C |
Informationen zur Lagerung | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution. |
Haltbarkeit | 12 months |
Bilder des Herstellers |
Produkt verwendet in: |
Dhuys, Claes, Van Loy, Schols: "CXCR7/ACKR3-targeting ligands interfere with X7 HIV-1 and HIV-2 entry and replication in human host cells." in: Heliyon, Vol. 4, Issue 3, pp. e00557, 2018 (PubMed).
Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human). Zhang, Qiu, Zhang, Xu, Zheng, Jiang: "CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells." in: Scientific reports, Vol. 7, Issue 1, pp. 8289, 2017 (PubMed). Von den Autoren verwendete Methode: Biochemical Assay (BCA), Biochemical Assay (BCA) (Probematerial (Species): Human). Cheng, Eby, LaPorte, Volkman, Majetschak: "Effects of cognate, non-cognate and synthetic CXCR4 and ACKR3 ligands on human lung endothelial cell barrier function." in: PLoS ONE, Vol. 12, Issue 11, pp. e0187949, 2017 (PubMed). Von den Autoren verwendete Methode: Functional Studies (Func), Functional Studies (Func) (Probematerial (Species): Human). Hira, Verbovšek, Breznik, Srdič, Novinec, Kakar, Wormer, der Swaan, Lenarčič, Juliano, Mehta, Van Noorden, Lah: "Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 3, pp. 594-603, 2017 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human). Montpas, St-Onge, Nama, Rhainds, Benredjem, Girard, Hickson, Pons, Heveker: "Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging." in: The Journal of biological chemistry, Vol. 293, Issue 3, pp. 893-905, 2017 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human). Mühlethaler-Mottet, Liberman, Ascenção, Flahaut, Balmas Bourloud, Yan, Jauquier, Gross, Joseph: "The CXCR4/CXCR7/CXCL12 Axis Is Involved in a Secondary but Complex Control of Neuroblastoma Metastatic Cell Homing." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125616, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Probematerial (Species): Human). Liu, Carson-Walter, Walter: "Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e103938, 2015 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human). Walsh, Harper, Poole: "SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4." in: Cellular signalling, Vol. 27, Issue 1, pp. 37-46, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Human). Walters, Ebsworth, Berahovich, Penfold, Liu, Al Omran, Kioi, Chernikova, Tseng, Mulkearns-Hubert, Sinyuk, Ransohoff, Lathia, Karamchandani, Kohrt, Zhang, Powers, Jaen, Schall, Merchant, Recht, Brown: "Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats." in: British journal of cancer, Vol. 110, Issue 5, pp. 1179-88, 2014 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human). Ding, Cao, Lis, Nolan, Guo, Simons, Penfold, Shido, Rabbany, Rafii: "Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis." in: Nature, Vol. 505, Issue 7481, pp. 97-102, 2014 (PubMed). Von den Autoren verwendete Methode: Immunoprecipitation (IP), Immunoprecipitation (IP), Immunoprecipitation (IP) (Probematerial (Species): Human). Boudot, Kerdivel, Lecomte, Flouriot, Desille, Godey, Leveque, Tas, Le Dréan, Pakdel: "COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration." in: BMC cancer, Vol. 14, pp. 407, 2014 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Human). Liberman, Sartelet, Flahaut, Mühlethaler-Mottet, Coulon, Nyalendo, Vassal, Joseph, Gross: "Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma." in: PLoS ONE, Vol. 7, Issue 8, pp. e43665, 2012 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human). Canals, Scholten, de Munnik, Han, Smit, Leurs: "Ubiquitination of CXCR7 controls receptor trafficking." in: PLoS ONE, Vol. 7, Issue 3, pp. e34192, 2012 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human). Naumann, Cameroni, Pruenster, Mahabaleshwar, Raz, Zerwes, Rot, Thelen: "CXCR7 functions as a scavenger for CXCL12 and CXCL11." in: PLoS ONE, Vol. 5, Issue 2, pp. e9175, 2010 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human). |