CXCR7 Antikörper (Chemokine (C-X-C Motif) Receptor 7)

Details for Product anti-CXCR7 Antibody No. ABIN4900748, Anbieter: Anmelden zum Anzeigen
Antigen
  • BEST:LD12308
  • CG3171
  • Dmel\\CG3171
  • LD12308
  • Tre-1
  • anon-WO0170980.16
  • anon-WO0170980.17
  • anon-WO0170981.1
  • sctt
  • tre-1
  • tre1
  • CMKOR1
  • CXC-R7
  • CXCR-7
  • CXCR7
  • GPR159
  • RDC-1
  • RDC1
  • AW541270
  • Cmkor1
  • Cxcr7
  • Rdc1
  • Trapped in endoderm 1
  • ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74
  • atypical chemokine receptor 3
  • Tre1
  • MmrVgp88
  • ACKR3
  • Ackr3
Reaktivität
Human
227
126
104
25
24
21
8
7
4
4
4
4
1
1
1
1
1
1
1
Wirt
Maus
162
74
11
7
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser CXCR7 Antikörper ist unkonjugiert
16
12
10
9
9
8
8
8
8
7
7
7
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
134
131
66
57
55
33
26
23
8
6
5
4
3
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Human CXCR7 encoding plasmid, Accession # P25106
Klon 11G8
Isotyp IgG1
Spezifität Detects human CXCR7/RDC-1 in flow cytometry of five distinct human CXCR7 transfectants, but not their respective parental lines.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Plasmids, Primers & others Plasmide, Primers & weitere CXCR7 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CXCR7 (CXCR7 Antibody Abstract)
Hintergrund Alternative Names: ACKR3, chemokine (C-X-C motif) receptor 7, Chemokine orphan receptor 1CMKOR1C-X-C chemokine receptor type 7, CMKOR1, CXCR7, CXC-R7, CXCR-7, G protein-coupled receptor, GPR159, GPR159G-protein coupled receptor 159, RDC-1, RDC1G-protein coupled receptor RDC1 homolog
Gen-ID 57007
UniProt P25106
Pathways Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling
Applikations-hinweise Flow Cytometry 0.25 μg/10^6 cells
Immunohistochemistry 8-25 μg/mL
CyTOF-ready
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungs-mittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (ABIN4900748) Detection of CXCR7/RDC-1 in MCF-7 Human Cell Line by Flow Cytometry. MCF-7 human brea...
Immunohistochemistry (IHC) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (ABIN4900748) CXCR7/RDC-1 in Human Breast Cancer Tissue in a Mouse Model. CXCR7/RDC-1 was detected ...
Immunohistochemistry (IHC) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (ABIN4900748) CXCR7/RDC-1 in Human Squamous Cell Carcinoma. CXCR7/RDC-1 was detected in immersion f...
Produkt verwendet in: Dhuys, Claes, Van Loy, Schols: "CXCR7/ACKR3-targeting ligands interfere with X7 HIV-1 and HIV-2 entry and replication in human host cells." in: Heliyon, Vol. 4, Issue 3, pp. e00557, 2018 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Zhang, Qiu, Zhang, Xu, Zheng, Jiang: "CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells." in: Scientific reports, Vol. 7, Issue 1, pp. 8289, 2017 (PubMed). Von den Autoren verwendete Methode: Biochemical Assay (BCA), Biochemical Assay (BCA) (Probematerial (Species): Human).

Cheng, Eby, LaPorte, Volkman, Majetschak: "Effects of cognate, non-cognate and synthetic CXCR4 and ACKR3 ligands on human lung endothelial cell barrier function." in: PLoS ONE, Vol. 12, Issue 11, pp. e0187949, 2017 (PubMed). Von den Autoren verwendete Methode: Functional Studies (Func), Functional Studies (Func) (Probematerial (Species): Human).

Hira, Verbovšek, Breznik, Srdič, Novinec, Kakar, Wormer, der Swaan, Lenarčič, Juliano, Mehta, Van Noorden, Lah: "Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 3, pp. 594-603, 2017 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Montpas, St-Onge, Nama, Rhainds, Benredjem, Girard, Hickson, Pons, Heveker: "Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging." in: The Journal of biological chemistry, Vol. 293, Issue 3, pp. 893-905, 2017 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Mühlethaler-Mottet, Liberman, Ascenção, Flahaut, Balmas Bourloud, Yan, Jauquier, Gross, Joseph: "The CXCR4/CXCR7/CXCL12 Axis Is Involved in a Secondary but Complex Control of Neuroblastoma Metastatic Cell Homing." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125616, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Probematerial (Species): Human).

Liu, Carson-Walter, Walter: "Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e103938, 2015 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human).

Walsh, Harper, Poole: "SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4." in: Cellular signalling, Vol. 27, Issue 1, pp. 37-46, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Human).

Walters, Ebsworth, Berahovich, Penfold, Liu, Al Omran, Kioi, Chernikova, Tseng, Mulkearns-Hubert, Sinyuk, Ransohoff, Lathia, Karamchandani, Kohrt, Zhang, Powers, Jaen, Schall, Merchant, Recht, Brown: "Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats." in: British journal of cancer, Vol. 110, Issue 5, pp. 1179-88, 2014 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Ding, Cao, Lis, Nolan, Guo, Simons, Penfold, Shido, Rabbany, Rafii: "Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis." in: Nature, Vol. 505, Issue 7481, pp. 97-102, 2014 (PubMed). Von den Autoren verwendete Methode: Immunoprecipitation (IP), Immunoprecipitation (IP), Immunoprecipitation (IP) (Probematerial (Species): Human).

Boudot, Kerdivel, Lecomte, Flouriot, Desille, Godey, Leveque, Tas, Le Dréan, Pakdel: "COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration." in: BMC cancer, Vol. 14, pp. 407, 2014 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Human).

Liberman, Sartelet, Flahaut, Mühlethaler-Mottet, Coulon, Nyalendo, Vassal, Joseph, Gross: "Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma." in: PLoS ONE, Vol. 7, Issue 8, pp. e43665, 2012 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human).

Canals, Scholten, de Munnik, Han, Smit, Leurs: "Ubiquitination of CXCR7 controls receptor trafficking." in: PLoS ONE, Vol. 7, Issue 3, pp. e34192, 2012 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human).

Naumann, Cameroni, Pruenster, Mahabaleshwar, Raz, Zerwes, Rot, Thelen: "CXCR7 functions as a scavenger for CXCL12 and CXCL11." in: PLoS ONE, Vol. 5, Issue 2, pp. e9175, 2010 (PubMed). Von den Autoren verwendete Methode: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Probematerial (Species): Human).

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