AXL Antikörper (AXL Receptor tyrosine Kinase) (pTyr779)

Details for Product anti-AXL Antibody No. ABIN4900635
Antigen
  • JTK11
  • UFO
  • AI323647
  • Ark
  • Tyro7
  • Ufo
  • AXL receptor tyrosine kinase
  • Axl receptor tyrosine kinase
  • AXL
  • Axl
Epitop
pTyr779
27
26
19
17
17
16
15
13
10
10
7
7
6
5
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
236
104
85
5
2
2
1
1
1
1
Wirt
Maus
203
46
3
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser AXL Antikörper ist unkonjugiert
15
10
8
8
8
7
7
7
7
7
7
6
2
2
2
2
2
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Simple Western (SimWes), Western Blotting (WB)
167
121
66
32
26
22
14
10
6
4
3
2
1
1
1
Optionen
Immunogen Phosphopeptide containing the human Axl Y779 site
Klon 713610
Isotyp IgG1
Spezifität Detects human Phospho-Axl (Y779) in direct ELISAs and Western blots.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Plasmids, Primers & others Plasmide, Primers & weitere AXL products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Axl (AXL Antibody Abstract)
Hintergrund Alternative Names: Ark, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming sequence/gene, EC 2.7.10, EC 2.7.10.1, JTK11, tyrosine-protein kinase receptor UFO, Ufo, UFOoncogene AXL
Gen-ID 558
Pathways RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
Applikations-hinweise Western Blot 0.2 μg/mL
Simple Western 4 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Sterile PBS to a final concentration of 0.5 mg/mL.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungs-mittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Simple Western (SimWes) image for anti-AXL Receptor tyrosine Kinase (AXL) (pTyr779) antibody (ABIN4900635) Detection of Human Phospho-Axl (Y779) by Simple WesternTM. Simple Western lane view s...
Western Blotting (WB) image for anti-AXL Receptor tyrosine Kinase (AXL) (pTyr779) antibody (ABIN4900635) Detection of Human Phospho-Axl (Y779) by Western Blot. Western blot shows lysates of ...
Flow Cytometry (FACS) image for anti-AXL Receptor tyrosine Kinase (AXL) (pTyr779) antibody (ABIN4900635) Detection of Phospho-Axl (Y779) in A172 Human Cell Line by Flow Cytometry. A172 human...
Immunocytochemistry (ICC) image for anti-AXL Receptor tyrosine Kinase (AXL) (pTyr779) antibody (ABIN4900635) Phospho-Axl (Y779) in A172 Human Cell Line. Axl phosphorylated at Y779 and total Axl ...
Produkt verwendet in: Dumas, Naudin, Martin-Lannerée, Izac, Casetti, Mansier, Rousseau, Artus, Dufossée, Giese, Dubus, Pigneux, Praloran, Bidet, Villacreces, Guitart, Milpied, Kosmider, Vigon, Desplat, Dusanter-Fourt et al.: "Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. ..." in: Haematologica, 2019 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Mori, Kaneko, Ueno, Yamada, Tanaka, Saito, Shimada, Mori, Kuromitsu: "Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia." in: Investigational new drugs, Vol. 35, Issue 5, pp. 556-565, 2018 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

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