FZD2 Antikörper (AA 267-279)

Produktnummer ABIN490012

Produktdetails anti-FZD2 Antikörper

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Bindungsspezifität: AA 267-279

Reaktivität: Human, Ratte, Maus, Pferd, Rind (Kuh), Hund, Hamster, Schwein, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FZD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human FZD2 / Frizzled 2.

Homologie: Percent identity by BLAST analysis: Human, Monkey, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Horse, Pig, Opossum (100%) Rabbit, Lizard (92%) Gorilla, Xenopus, Newt (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide RYATLEHPFHCPR from an internal region of human FZD2 / Frizzled 2 (NP_001457.1). Percent identity by BLAST analysis: Human, Monkey, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Horse, Pig, Opossum (100%), Rabbit, Lizard (92%), Gorilla, Xenopus, Newt (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:64000)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Preliminary experiments gave an approx. 23kD band in Human Colon, Heart and Ovary lysates after 0.1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 63.6kD according to NP_001457.1. The 23kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu FZD2

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Andere Bezeichnung: FSD2 / Frizzled 2 (FZD2 Produkte)

Synonyme: BG01711 antikoerper, CG9739 antikoerper, D-Fz2 antikoerper, D-fz2 antikoerper, DFZ2 antikoerper, DFz-2 antikoerper, DFz2 antikoerper, Dfrz2 antikoerper, Dfz2 antikoerper, Dfz[[2]] antikoerper, Dm Fz2 antikoerper, Dmel\\CG9739 antikoerper, FZ2 antikoerper, Fz2 antikoerper, dFz2 antikoerper, dfz(2) antikoerper, dfz2 antikoerper, dfz2r antikoerper, frz2 antikoerper, fz-2 antikoerper, fz8 antikoerper, zfz2 antikoerper, zg08 antikoerper, cb383 antikoerper, wu:fb70g09 antikoerper, FZD2 antikoerper, fzE2 antikoerper, hFz2 antikoerper, Fz-10 antikoerper, Fzd10 antikoerper, cFz-2 antikoerper, frizzled2 antikoerper, fz2 antikoerper, xfz2 antikoerper, AL033370 antikoerper, AW456835 antikoerper, Fz10 antikoerper, Mfz10 antikoerper, Mfz10a antikoerper, frizzled 2 antikoerper, frizzled class receptor 2 antikoerper, frizzled class receptor 2 S homeolog antikoerper, fz2 antikoerper, fzd2 antikoerper, FZD2 antikoerper, Fzd2 antikoerper, fzd2.S antikoerper

Hintergrund: Name/Gene ID: FZD2
Subfamily: Frizzled
Family: GPCR

Synonyms: FZD2, Dfrizzled2, Fz2, Frizzled family receptor 2, Frizzled-2, HFz2, Frizzled homolog 2, Fz-2, FzE2, Mfz10, Rfz2, Frizzled 2

Gen-ID: 2535

NCBI Accession: NP_001457

UniProt: Q14332

Pathways: WNT Signalweg