TEK Antikörper (TEK Tyrosine Kinase, Endothelial) (AA 23-745)

Details for Product anti-TEK Antibody No. ABIN4899775
Antigen
Epitop
AA 23-745
29
26
22
20
16
15
11
10
10
8
8
8
6
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
283
161
97
8
8
Wirt
Maus
231
62
7
3
2
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser TEK Antikörper ist unkonjugiert
20
14
9
8
8
8
8
8
8
7
6
4
4
4
4
4
4
1
Applikation
Flow Cytometry (FACS), Western Blotting (WB)
176
138
61
53
47
28
21
17
10
9
9
8
4
2
Optionen
Immunogen Mouse myeloma cell line NS0-derived recombinant human Tie-2, Ala23-Lys745, Accession # AAA61139
Klon 83715
Isotyp IgG1
Spezifität Detects human Tie-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tie-1, recombinant mouse Tie-2, or recombinant zebrafish Tie-2 is observed.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Antigen
Andere Bezeichnung Tie-2 (TEK Antibody Abstract)
Hintergrund Alternative Names: angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1
Gen-ID 7010
Pathways RTK Signalweg, Growth Factor Binding
Applikations-hinweise Western Blot 1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in Tris and NaCl with Trehalose.
Konservierungs-mittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Image no. 1 for anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 23-745) antibody (ABIN4899775) Detection of Tie-2 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein...
Produkt verwendet in: Riccioni, Senese, Diverio, Riti, Mariani, Boe, LoCoco, Foà, Peschle, Sporn, Testa: "Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels." in: Leukemia research, Vol. 32, Issue 8, pp. 1244-58, 2008 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Riccioni, Diverio, Mariani, Buffolino, Riti, Saulle, Petrucci, Cedrone, Lo-Coco, Foà, Peschle, Testa: "Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 8, pp. 1862-71, 2007 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Ponte, Marais, Gallay, Langonné, Delorme, Hérault, Charbord, Domenech: "The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 7, pp. 1737-45, 2007 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Danet, Pan, Luongo, Bonnet, Simon: "Expansion of human SCID-repopulating cells under hypoxic conditions." in: The Journal of clinical investigation, Vol. 112, Issue 1, pp. 126-35, 2003 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).