RHOH Antikörper (C-Term)

Produktnummer ABIN4889497

Produktdetails anti-RHOH Antikörper

Target: RHOH (Ras Homolog Family Member H (RHOH))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Reacts with human RhoH protein

Aufreinigung: Purified (protein A)

Immunogen: Synthetic peptide derived from C terminal domain of human RhoH

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- IHC : 1/200 to 1/2 000 - WB : 1/500 to 1/5 000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu RHOH

Target: RHOH (Ras Homolog Family Member H (RHOH))

Andere Bezeichnung: rho-Related GTP-Binding Protein RhoH (RHOH Produkte)

Synonyme: ARHH antikoerper, TTF antikoerper, 5830400A04Rik antikoerper, AU019774 antikoerper, Arhh antikoerper, ras homolog family member H antikoerper, RHOH antikoerper, Rhoh antikoerper

Hintergrund: Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection.

UniProt: Q15669