UNC5B Antikörper

Produktnummer ABIN4889372

Produktdetails anti-UNC5B Antikörper

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Reacts with human, mouse, rat UNC5B

Aufreinigung: Purified (protein A)

Immunogen: UNC5B human recombinant protein

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:5000) IHC(1:100 - 1:500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water to reach 1 mg/mL

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu UNC5B

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Andere Bezeichnung: Netrin Receptor UNC5B (UNC5B Produkte)

Synonyme: unc5h2 antikoerper, 6330415E02Rik antikoerper, A630020F16 antikoerper, D10Bwg0792e antikoerper, Unc5h2 antikoerper, UNC5H2 antikoerper, p53RDL1 antikoerper, UNC5C antikoerper, UNC5B antikoerper, p53rdl1 antikoerper, unc-5 netrin receptor B antikoerper, unc-5 netrin receptor B L homeolog antikoerper, unc5b antikoerper, Unc5b antikoerper, UNC5B antikoerper, unc5b.L antikoerper

Hintergrund: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity

UniProt: Q8IZJ1