WWP1 Antikörper (Internal Region)

Produktnummer ABIN4889365

Produktdetails anti-WWP1 Antikörper

Target: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Reacts with human WWP1 protein

Aufreinigung: Purified (protein A)

Immunogen: Synthetic peptide derived from internal part of human WWP1 protein

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
WB(1:200 - 1:2000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu WWP1

Target: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Andere Bezeichnung: NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1 Produkte)

Synonyme: AIP5 antikoerper, Tiul1 antikoerper, hSDRP1 antikoerper, 8030445B08Rik antikoerper, SDRP1 antikoerper, WWP1 antikoerper, aip5 antikoerper, tiul1 antikoerper, hsdrp1 antikoerper, WW domain containing E3 ubiquitin protein ligase 1 antikoerper, WWP1 antikoerper, Wwp1 antikoerper, wwp1 antikoerper

Hintergrund: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF

UniProt: Q9H0M0