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SAFB Antikörper (C-Term)

SAFB Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886716
  • Target Alle SAFB Antikörper anzeigen
    SAFB (Scaffold Attachment Factor B (SAFB))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 715-754, C-Term
    Reaktivität
    • 40
    • 22
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 10
    Kaninchen
    Klonalität
    • 44
    • 11
    Polyklonal
    Konjugat
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SAFB Antikörper ist unkonjugiert
    Applikation
    • 38
    • 21
    • 14
    • 14
    • 13
    • 12
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Scaffold attachment factor B1(SAFB) detection. Tested with WB in Human.
    Sequenz
    DLDRRDDAYW PEAKRAALDE RYHSDFNRQD RFHDFDHRDR
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Scaffold attachment factor B1(SAFB) detection. Tested with WB in Human.
    Gene Name: scaffold attachment factor B
    Protein Name: Scaffold attachment factor B1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human SAFB (715-754aa DLDRRDDAYWPEAKRAALDERYHSDFNRQDRFHDFDHRDR), different from the related mouse and rat sequences by five amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product SAFB Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    SAFB (Scaffold Attachment Factor B (SAFB))
    Andere Bezeichnung
    SAFB (SAFB Produkte)
    Synonyme
    HAP antikoerper, HET antikoerper, SAF-B1 antikoerper, SAFB1 antikoerper, 3110021E02Rik antikoerper, 5330423C17Rik antikoerper, AU018122 antikoerper, D18386 antikoerper, E130307D12 antikoerper, zgc:55387 antikoerper, wu:fb40a03 antikoerper, wu:fd42g06 antikoerper, SAFB2 antikoerper, SAFB antikoerper, scaffold attachment factor B antikoerper, scaffold attachment factor B S homeolog antikoerper, SAFB-like transcription modulator antikoerper, Scaffold attachment factor B antikoerper, SAFB antikoerper, Safb antikoerper, safb antikoerper, safb.S antikoerper, LOC5570070 antikoerper, CpipJ_CPIJ017179 antikoerper, Bm1_49330 antikoerper, LOAG_00080 antikoerper
    Hintergrund
    Scaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice. This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.

    Synonyms: HAP | HET | SAF B | SAF-B | SAF-B1 | SAFB 1 | SAFB | SAFB1 | Q15424
    Gen-ID
    6294
    UniProt
    Q15424
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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