GNB1 Antikörper (N-Term)

Produktnummer ABIN4886607

Produktdetails anti-GNB1 Antikörper

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Bindungsspezifität: AA 2-42, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(GNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: SELDQLRQEA EQLKNQIRDA RKACADATLS QITNNIDPVG R

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(GNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: G protein subunit beta 1
Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human GNB1 (2-42aa SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu GNB1

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Andere Bezeichnung: GNB1 (GNB1 Produkte)

Synonyme: gnb1 antikoerper, wu:fb50b09 antikoerper, wu:fj94h04 antikoerper, AA409223 antikoerper, C77571 antikoerper, Gnb-1 antikoerper, XGB1 antikoerper, xgbeta1 antikoerper, GNB1x antikoerper, fb39f01 antikoerper, gnb1l antikoerper, wu:fb39f01 antikoerper, wu:fb98e06 antikoerper, wu:fj09d12 antikoerper, zgc:55774 antikoerper, G protein subunit beta 1 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 1a antikoerper, guanine nucleotide binding protein (G protein), beta 1 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 1 S homeolog antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 1b antikoerper, GNB1 antikoerper, gnb1a antikoerper, Gnb1 antikoerper, gnb1.S antikoerper, gnb1b antikoerper

Hintergrund: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals.

Synonyms: G protein beta 1 subunit | GBB1 | gnb1 | P62873

Gen-ID: 2782

UniProt: P62873

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interaktom