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ERCC6 Antikörper (N-Term)

ERCC6 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886573
  • Target Alle ERCC6 Antikörper anzeigen
    ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-205, N-Term
    Reaktivität
    • 33
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 43
    • 4
    • 1
    Kaninchen
    Klonalität
    • 45
    • 3
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERCC6 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 22
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for DNA excision repair protein ERCC-6(ERCC6) detection. Tested with WB in Human,Rat.
    Sequenz
    QAATSRDINR KLDSVKRQKY NKEQQLKKIT AKQKHLQAIL GGAEVK
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for DNA excision repair protein ERCC-6(ERCC6) detection. Tested with WB in Human,Rat.
    Gene Name: ERCC excision repair 6, chromatin remodeling factor
    Protein Name: DNA excision repair protein ERCC-6
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human CSB (160-205aa QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK).
    Isotyp
    IgG
    Top Product
    Discover our top product ERCC6 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))
    Andere Bezeichnung
    ERCC6 (ERCC6 Produkte)
    Synonyme
    ARMD5 antikoerper, CKN2 antikoerper, COFS antikoerper, COFS1 antikoerper, CSB antikoerper, RAD26 antikoerper, UVSS1 antikoerper, 4732403I04 antikoerper, C130058G22Rik antikoerper, ercc6 antikoerper, Ercc6 antikoerper, ERCC excision repair 6, chromatin remodeling factor antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 6 antikoerper, excision repair cross-complementation group 6 antikoerper, DNA excision repair protein ERCC-6 antikoerper, ERCC6 antikoerper, Ercc6 antikoerper, ercc6 antikoerper, LOC100719487 antikoerper
    Hintergrund
    DNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

    Synonyms: ARMD 5 | ARMD5 | CKN 2 | CKN2 | COFS | COFS1 | CSB | ERCC 6 | ERCC6 | RAD26 | UVSS1 | Q03468
    Gen-ID
    2074
    UniProt
    Q03468
    Pathways
    DNA Reparatur, Chromatin Binding
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