SLC29A1 Antikörper (Middle Region)

Produktnummer ABIN5551992

Produktdetails anti-SLC29A1 Antikörper

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC29A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to ENT1 (Center).

Aufreinigung: Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ENT1 (Slc29a1).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1-50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-SLC29A1 Antikörper (ABIN5551992)

Wang, Word, Lyn-Cook: "Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrative nucleoside transporter 1." in: Anticancer research, Vol. 31, Issue 10, pp. 3171-80, (2011) (PubMed).

Details zu SLC29A1

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Andere Bezeichnung: SLC29A1 / ENT1 (SLC29A1 Produkte)

Synonyme: ENT1 antikoerper, rENT1 antikoerper, 1200014D21Rik antikoerper, AA407560 antikoerper, solute carrier family 29 member 1 (Augustine blood group) antikoerper, solute carrier family 29 member 1 antikoerper, solute carrier family 29 (nucleoside transporters), member 1 antikoerper, SLC29A1 antikoerper, Slc29a1 antikoerper

Hintergrund: ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.Synonyms: Equilibrative nucleoside transporter 1, Solute carrier family 29 member 1

Gen-ID: 2030, 9606

UniProt: Q99808

Pathways: Carbohydrate Homeostasis, Synaptic Membrane