PPAP2B Antikörper

Produktnummer ABIN4620345

Produktdetails anti-PPAP2B Antikörper

Target: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAP2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Phosphatidic Acid Phosphatase 2B .

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide derived from the phosphatidic acid phosphatase 2B protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot. Enzyme Immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Ship on dry ice. Store (in aliquots) at -20 °C to -70 °C.

Details zu PPAP2B

Target: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Andere Bezeichnung: PPAP2B / LPP3 (PPAP2B Produkte)

Synonyme: Dri42 antikoerper, LPP3 antikoerper, PAP2B antikoerper, VCIP antikoerper, 1110003O22Rik antikoerper, 2610002D05Rik antikoerper, AV025606 antikoerper, D4Bwg0538e antikoerper, D4Bwg1535e antikoerper, Lpp3 antikoerper, Ppab2b antikoerper, dri42 antikoerper, lpp3 antikoerper, pap2b antikoerper, ppap2bb antikoerper, vcip antikoerper, ppap2b antikoerper, ppap2ba antikoerper, PPAP2B antikoerper, si:dkey-19f4.1 antikoerper, phospholipid phosphatase 3 antikoerper, phospholipid phosphatase 3 L homeolog antikoerper, phospholipid phosphatase 3 S homeolog antikoerper, PLPP3 antikoerper, Plpp3 antikoerper, plpp3.L antikoerper, plpp3.S antikoerper, plpp3 antikoerper

Hintergrund: Vascular endothelial growth factor and type I collagen inducible protein (VCIP), also known as phosphatidic acid phosphatase 2b (PAP2b), was originally identified in a functional assay of angiogenesis. VCIP/PAP2b exhibits an Arg - Gly - Asp (RGD) cell adhesion sequence. Immunoprecipitation and fluorescence-activated cell sorting analyses demonstrated that VCIP-RGD is exposed to the outside of the cell surface. Retroviral transduction of VCIP can induce cell aggregation and cell-cell interactions, modestly increase p120 catenin expression and promote activation of the Fak, Akt and GSK3ß protein kinases. Expression of VCIP promoted adhesion, spreading and tyrosine phosphorylation of Fak, Shc, Cas and paxillin in endothelial cells. PAP2b/VCIP is expressed in close proximity to vascular endothelial growth factor, von Willebrand factor and {alpha}vbeta3 integrin in tumor vasculatures.Synonyms: Lipid phosphate phosphohydrolase 3, PAP2-beta, PAP2B, Phosphatidate phosphohydrolase type 2b, Phosphatidic acid phosphatase 2b, VCIP, Vascular endothelial growth factor and type I collagen-inducible protein

Gen-ID: 8613

NCBI Accession: NP_003704

UniProt: O14495