kappa Light Chain Antikörper

Produktnummer ABIN457414

Produktdetails anti-kappa Light Chain Antikörper

Target: kappa Light Chain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser kappa Light Chain Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.

Keine Kreuzreaktivität: Ziege, Meerschweinchen, Hamster, Kaninchen, Schaf

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Klon: A8B5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL, Positive control: Daudi human cell line.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-kappa Light Chain Antikörper (ABIN457414)

Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, (2008) (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, (1999) (PubMed).

Details zu kappa Light Chain

Target: kappa Light Chain

Andere Bezeichnung: Kappa light chains (kappa Light Chain Produkte)

Synonyme: LOC100037688 antikoerper, B128L antikoerper, B55L antikoerper, IgK antikoerper, TCRAV31S1 antikoerper, TCRAV40S1 antikoerper, kappa light chain antikoerper, immunoglobulin kappa chain variable 8 (V8) antikoerper, T cell receptor alpha variable 40 antikoerper, LOC100037688 antikoerper, Igk-V8 antikoerper, TRAV40 antikoerper

Hintergrund: Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin kappa, Igk