SLC11A1 Antikörper (Middle Region)

Produktnummer ABIN453379

Produktdetails anti-SLC11A1 Antikörper

Target: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC11A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes NRAMP1/SLC11A1 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: KLH conjugated synthetic peptide selected from the Center region of Human NRAMP1/SLC11A1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SLC11A1

Target: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Andere Bezeichnung: NRAMP1 (SLC11A1 Produkte)

Synonyme: SLC11A1 antikoerper, NRAMP1 antikoerper, LSH antikoerper, NRAMP antikoerper, Bcg antikoerper, Itg antikoerper, Lsh antikoerper, Nramp1 antikoerper, Ity antikoerper, Nramp antikoerper, ity antikoerper, BCG antikoerper, solute carrier family 11 member 1 L homeolog antikoerper, solute carrier family 11 member 1 antikoerper, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 antikoerper, slc11a1.L antikoerper, SLC11A1 antikoerper, Slc11a1 antikoerper

Hintergrund: NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.Synonyms: LSH, NRAMP, NRAMP-1, Natural resistance-associated macrophage protein 1, SLC11A1

Gen-ID: 6556

NCBI Accession: NP_000569

UniProt: P49279

Pathways: Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus