TLR9 Antikörper (Toll-Like Receptor 9)

Details for Product anti-TLR9 Antibody No. ABIN4360432, Anbieter: Anmelden zum Anzeigen
Antigen
  • CD289
  • toll like receptor 9
  • toll-like receptor 9
  • TLR9
  • Tlr9
Reaktivität
Hund, Pferd, Human, Maus, Primate, Ratte (Rattus)
261
147
54
35
22
19
7
5
3
2
2
2
2
2
1
1
Wirt
Maus
143
123
35
14
4
3
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser TLR9 Antikörper ist unkonjugiert
27
25
17
8
6
6
5
4
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), ELISA, Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), In vitro Assay (in vitro), Simple Western (SimWes), Western Blotting (WB)
227
162
132
108
88
38
37
36
13
6
6
6
6
5
4
3
2
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This antibody was developed against KLH-conjugated synthetic peptide corresponding to amino acids 268-300 of human TLR9 isoform A (Genbank accession no. AAF78037).
Klon 26C593-2
Isotyp IgG1 kappa
Reinigung Protein G purified
Sterilität Sterile filtered
Plasmids, Primers & others Plasmide, Primers & weitere TLR9 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung TLR9
Hintergrund Gene Symbol: TLR9
Gen-ID 54106
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Applikations-hinweise Western Blot 2-5 μg/mL, Simple Western 30 μg/mL, Flow Cytometry 1 μL/1 million cells, ELISA 1:100 - 1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10 - 1:500, Immunohistochemistry-Paraffin 5 μg/mL, Functional, In vitro assay, Flow (Intracellular) 1:10 - 1:1000, CyTOF-readyStaining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min. In human PBMC, a ~120 kDa band is observed. A smaller isoform, TLR9 isoform B (Genbank accession no. AAF72190) containing 975 amino acids may also be observed in some cases.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Sterile - filtered PBS
Buffer contains: No Preservative
Konservierungs-mittel Without preservative
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze-thaw cycles.
Produkt verwendet in: Guerrier, Pochard, Lahiri, Youinou, Pers, Jamin: "TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response." in: Journal of autoimmunity, Vol. 51, pp. 23-9, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: In vitro Assay

Abdi, Mutis, Garssen, Redegeld: "Characterization of the Toll-like receptor expression profile in human multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e60671, 2013 (PubMed).

Figueiredo, Amorim, Pinto, Barbosa, Pinheiro, Deoti, Faria, Tafuri: "Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum." in: BMC immunology, Vol. 14, pp. 22, 2013 (PubMed).

Belmont, Rabbe, Antoine, Cathelin, Guignabert, Kurie, Cadranel, Wislez: "Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer." in: International journal of cancer, Vol. 134, Issue 4, pp. 765-77, 2013 (PubMed).

Siponen, Kauppila, Soini, Salo: "TLR4 and TLR9 are induced in oral lichen planus." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 41, Issue 10, pp. 741-7, 2012 (PubMed).

Schneberger, Lewis, Caldwell, Singh: "Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle." in: International journal of experimental pathology, Vol. 92, Issue 1, pp. 1-7, 2011 (PubMed).

Myles, Aggarwal: "Expression of Toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis." in: Rheumatology (Oxford, England), Vol. 50, Issue 3, pp. 481-8, 2011 (PubMed).

van Gent, Griffin, Berkhoff, van Leeuwen, Boer, Buisson, Hartgers, Burmeister, Wiertz, Ressing: "EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 3, pp. 1694-702, 2011 (PubMed).

Dasgupta, Chentoufi, You, Falatoonzadeh, Urbano, Akhtarmalik, Nguyen, Ablabutyan, Nesburn, BenMohamed: "Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses." in: Investigative ophthalmology & visual science, Vol. 52, Issue 6, pp. 3321-33, 2011 (PubMed).

Karim, Meyers, Backendorf, Ludigs, Offringa, van Ommen, Melief, van der Burg, Boer: "Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes." in: PLoS ONE, Vol. 6, Issue 3, pp. e17848, 2011 (PubMed).

Wu, Meng, Jiang, Zhang, Trippler, Broering, Bucchi, Krux, Dittmer, Yang, Roggendorf, Gerken, Lu, Schlaak: "Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific." in: Immunology, Vol. 129, Issue 3, pp. 363-74, 2010 (PubMed).

Chentoufi, Dasgupta, Nesburn, Bettahi, Binder, Choudhury, Chamberlain, Wechsler, BenMohamed: "Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization." in: Clinical and vaccine immunology : CVI, Vol. 17, Issue 3, pp. 342-53, 2010 (PubMed).

Panda, Qian, Mohanty, van Duin, Newman, Zhang, Chen, Towle, Belshe, Fikrig, Allore, Montgomery, Shaw: "Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 5, pp. 2518-27, 2010 (PubMed).

Kim, Park, Brand, Fitzpatrick, Yi: "Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 6, pp. 3145-56, 2010 (PubMed).

Machida, Ito, Hirose, Takeshita, Oshiro, Nakamura, Mori, Inayama, Yan, Kobayashi, Yokota: "Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 25, Issue 8, pp. 2530-537, 2010 (PubMed).

Jukkola-Vuorinen, Rahko, Vuopala, Desmond, Lehenkari, Harris, Selander: "Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer." in: Journal of innate immunity, Vol. 1, Issue 1, pp. 59-68, 2010 (PubMed).

Keestra, de Zoete, Bouwman, van Putten: "Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 460-7, 2010 (PubMed).

Booth, Arsenault, Napper, Griebel, Potter, Babiuk, Mutwiri: "TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides." in: Journal of innate immunity, Vol. 2, Issue 5, pp. 483-94, 2010 (PubMed).

Wang, Cao, Yan, Ying, Jiang, Xu, Wu: "TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients." in: BMC cancer, Vol. 10, pp. 415, 2010 (PubMed).

Cognasse, Hamzeh-Cognasse, Lafarge, Chavarin, Pozzetto, Richard, Garraud: "Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6." in: Immunology, Vol. 125, Issue 3, pp. 430-7, 2009 (PubMed).

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