TLR8 Antikörper (Toll-Like Receptor 8)

Details for Product anti-TLR8 Antibody No. ABIN4360386
  • CD288
  • toll like receptor 8
  • toll-like receptor 8
  • TLR8
  • Tlr8
Human, Maus
Klonalität (Klon)
Monoklonal ()
Dieser TLR8 Antikörper ist unkonjugiert
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Simple Western (SimWes), Western Blotting (WB)
Immunogen This antibody was developed against a KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850.
Klon 44C143
Isotyp IgG1 kappa
Reinigung Protein G purified
Plasmids, Primers & others Plasmide, Primers & weitere TLR8 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung TLR8 (TLR8 Antibody Abstract)
Hintergrund Gene Symbol: TLR8
Gen-ID 51311
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Applikations-hinweise Western Blot 1-3 μg/mL, Simple Western 20 μg/mL, Flow Cytometry 0.5-1 μg/10^6 cells, Immunohistochemistry-Paraffin 5 μg/mL, Flow (Intracellular), CyTOF-readyStaining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min. Use in Flow-intracellular reported in scientific literature (PMID 24836676). In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer 0.1 mL PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Produkt verwendet in: Deng, Ge, Liu, Pang, Huang, Peng, Sun, Hou, Zhang: "Impaired expression and function of TLR8 in chronic HBV infection and its association with treatment responses during peg-IFN-α-2a antiviral therapy." in: Clinics and research in hepatology and gastroenterology, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC)

Huhta, Helminen, Kauppila, Salo, Porvari, Saarnio, Lehenkari, Karttunen: "The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 8, pp. 470-82, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Jeon, Kim, Koh, Chung, Ha: "Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination." in: Oncotarget, Vol. 7, Issue 27, pp. 41811-41824, 2016 (PubMed). Von den Autoren verwendete Methode: Dot Blot (DB) (Probematerial (Species): Human).

Helminen, Huhta, Kauppila, Lehenkari, Saarnio, Karttunen: "Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 2, pp. 85-92, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Human).

Chatillon, Hamieh, Bayeux, Abasq, Fauquembergue, Drouet, Guisier, Latouche, Musette: "Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies." in: Immunity, inflammation and disease, Vol. 3, Issue 1, pp. 1-13, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Flow Cytometry

Zimmermann, Aguilera, Castellucci, Rossato, Costa, Lunardi, Ostuni, Girolomoni, Natoli, Bazzoni, Tamassia, Cassatella: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." in: Nature communications, Vol. 6, pp. 6061, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Jamin, Dehoux, Dossier, Fila, Heming, Monteiro, Deschênes: "Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome." in: Clinical and experimental immunology, Vol. 182, Issue 3, pp. 332-45, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Bernard, Han, Inderbitzin, Agbim, Zhao, Koziel, Tachado: "HIV-derived ssRNA binds to TLR8 to induce inflammation-driven macrophage foam cell formation." in: PLoS ONE, Vol. 9, Issue 8, pp. e104039, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Flow Cytometry

Youn, Shim, Lee, Ji, Oh, Hong, Lee, Park, Lee, Choi, Chung, Kang: "Detailed pathologic evaluation on endomyocardial biopsy provides long-term prognostic information in patients with acute myocarditis." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 23, Issue 3, pp. 139-44, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Wang, Eng, Lin, Liu, Chang, Lin: "Functional polymorphisms of TLR8 are associated with hepatitis C virus infection." in: Immunology, Vol. 141, Issue 4, pp. 540-8, 2014 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Camacho-Sandoval, Del Río Estrada, Rivero-Arrieta, Reyes-Terán, Bonifaz: "Differential partial activation phenotype and production of tumour necrosis factor-α by conventional dendritic cells in response to lipopolysaccharide in HIV+ viraemic subjects and HIV+ controllers." in: Clinical and experimental immunology, Vol. 178, Issue 3, pp. 489-503, 2014 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Tengroth, Arebro, Kumlien Geor��n, Winqvist, Cardell: "Deprived TLR9 expression in apparently healthy nasal mucosa might trigger polyp-growth in chronic rhinosinusitis patients." in: PLoS ONE, Vol. 9, Issue 8, pp. e105618, 2014 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Green, Santos, Ejaeidi, Craft, Lewis, Cruse: "Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells." in: Experimental and molecular pathology, Vol. 97, Issue 1, pp. 44-8, 2014 (PubMed). Von den Autoren verwendete Methode: Intracellular Flow Cytometry (ICFC) (Probematerial (Species): Human).

Chamberlain, Kim, Vila, Volin, Volkov, Pope, Arami, Mandelin, Shahrara: "Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNFα in monocytes." in: Annals of the rheumatic diseases, Vol. 72, Issue 3, pp. 418-26, 2013 (PubMed).

Abdi, Mutis, Garssen, Redegeld: "Characterization of the Toll-like receptor expression profile in human multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e60671, 2013 (PubMed). Weitere Details: Western Blotting,Flow Cytometry,Immunochromatography

Berger, Hsieh, Bakele, Marcos, Rieber, Kormann, Mays, Hofer, Neth, Vitkov, Krautgartner, von Schweinitz, Kappler, Hector, Weber, Hartl: "Neutrophils express distinct RNA receptors in a non-canonical way." in: The Journal of biological chemistry, Vol. 287, Issue 23, pp. 19409-17, 2012 (PubMed). Weitere Details: Cell Sorting,Flow Cytometry,Immunochromatography

Harman, Bye, Nasr, Sandgren, Kim, Mercier, Botting, Lewin, Cunningham, Cameron: "Identification of lineage relationships and novel markers of blood and skin human dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 1, pp. 66-79, 2012 (PubMed).

Dasari, Zola, Nicholson: "Expression of Toll-like receptors by neonatal leukocytes." in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Vol. 22, Issue 2, pp. 221-8, 2011 (PubMed).

Dasgupta, Chentoufi, You, Falatoonzadeh, Urbano, Akhtarmalik, Nguyen, Ablabutyan, Nesburn, BenMohamed: "Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses." in: Investigative ophthalmology & visual science, Vol. 52, Issue 6, pp. 3321-33, 2011 (PubMed).

Pang, Bala, Kodys, Catalano, Szabo: "Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes." in: BMC immunology, Vol. 12, pp. 55, 2011 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

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