TLR3 Antikörper (Toll-Like Receptor 3)

Details for Product anti-TLR3 Antibody No. ABIN4360082
  • CD283
  • IIAE2
  • AI957183
  • zgc:123006
  • toll like receptor 3
  • toll-like receptor 3
  • TLR3
  • Tlr3
  • tlr3
Hund, Human, Maus
Klonalität (Klon)
Monoklonal ()
Dieser TLR3 Antikörper ist unkonjugiert
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Immunogen A synthetic peptide corresponding to amino acids 55-85 of human TLR3 was used as immunogen.
Klon 40C1285-6
Isotyp IgG1 kappa
Reinigung Protein G purified
Plasmids, Primers & others Plasmide, Primers & weitere TLR3 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung TLR3 (TLR3 Antibody Abstract)
Hintergrund Gene Symbol: TLR3
Gen-ID 7098
Pathways TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Applikations-hinweise Western Blot 1-3 μg/mL, Flow Cytometry 2-4 μg/ 1x10^6 cells, Immunohistochemistry 1:20-1:1000, Immunocytochemistry/Immunofluorescence 1:20-1:1000, Immunoprecipitation 2 μg/ 1x10^6 cells, Immunohistochemistry-Paraffin 1:20-1:1000, Flow (Intracellular)Use in Flow-intracellular reported in scientific literature (PMID 24836676)

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer 0.2 mL PBS and 0.05 % BSA
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Produkt verwendet in: Zhu, Message, Mallia, Kebadze, Contoli, Ward, Barnathan, Mascelli, Kon, Papi, Stanciu, Edwards, Jeffery, Johnston: "Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations." in: The Journal of allergy and clinical immunology, Vol. 143, Issue 1, pp. 114-125.e4, 2019 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Human).

Gao, Gao, Guan, Huang, Huang, Lin, Liu, Zhao, Huang, Yuan, Liu, Liang, Zhang, Ma, Li, Li, Zhou, Shi, Xu, Chen: "Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6197-6208, 2019 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Regel, Raulefs, Benitz, Mihaljevic, Rieder, Leinenkugel, Steiger, Schlitter, Esposito, Mayerle, Kong, Kleeff, Michalski: "Loss of TLR3 and its downstream signaling accelerates acinar cell damage in the acute phase of pancreatitis." in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 19, Issue 1, pp. 149-157, 2019 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Mouse (Murine)).

Igase, Shousu, Fujiki, Sakurai, Bonkobara, Hwang, Coffey, Noguchi, Nemoto, Mizuno: "Anti-tumour activity of oncolytic reovirus against canine histiocytic sarcoma cells." in: Veterinary and comparative oncology, Vol. 17, Issue 2, pp. 184-193, 2019 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Dog (Canine)).

Gu, Ding, Shi, Huang, Guo, Yu, Hu, Huang, Liao: "Calcium/Calmodulin-Dependent Protein Kinase IV Mediates IFN-γ-Induced Immune Behaviors in Skeletal Muscle Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 1, pp. 351-364, 2018 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Brempelis, Yuen, Schwarz, Mohar, Crispe: "Central role of the TIR-domain-containing adaptor-inducing interferon-β (TRIF) adaptor protein in murine sterile liver injury." in: Hepatology (Baltimore, Md.), Vol. 65, Issue 4, pp. 1336-1351, 2017 (PubMed). (Probematerial (Species): Mouse (Murine)).

Larsson, Tengroth, Xu, Uddman, Kumlien Georén, Cardell: "Substance P represents a novel first-line defense mechanism in the nose." in: The Journal of allergy and clinical immunology, 2017 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Mouse (Murine)).

Huhta, Helminen, Kauppila, Salo, Porvari, Saarnio, Lehenkari, Karttunen: "The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 8, pp. 470-82, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Zou, Su, Ruan, Shao, Qian, Ye, Qin: "Toll-like receptor 3 pathway restricts Marek's disease virus infection." in: Oncotarget, Vol. 8, Issue 41, pp. 70847-70853, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Yang, Wang, Huang, Zou, Yan, Luo, Wang: "The RNA-binding protein Mex3B is a coreceptor of Toll-like receptor 3 in innate antiviral response." in: Cell research, Vol. 26, Issue 3, pp. 288-303, 2016 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Helminen, Huhta, Kauppila, Lehenkari, Saarnio, Karttunen: "Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 2, pp. 85-92, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC)

Evangelista, Castro, Alves, Dias, Souza, Reis, Silva, Castañon, Farias, Juliano, Ferreira: "Early IFN-γ production together with decreased expression of TLR3 and TLR9 characterizes EAE development conditional on the presence of myelin." in: Autoimmunity, Vol. 49, Issue 4, pp. 258-67, 2016 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Mouse (Murine)).

Silva-Barrios, Smans, Duerr, Qureshi, Fritz, Descoteaux, Stäger: "Innate Immune B Cell Activation by Leishmania donovani Exacerbates Disease and Mediates Hypergammaglobulinemia." in: Cell reports, Vol. 15, Issue 11, pp. 2427-37, 2016 (PubMed). Von den Autoren verwendete Methode: Immunofluorescence (fixed cells) (IF/ICC) (Probematerial (Species): Mouse (Murine)).

Reins, Baidouri, McDermott: "Vitamin D Activation and Function in Human Corneal Epithelial Cells During TLR-Induced Inflammation." in: Investigative ophthalmology & visual science, Vol. 56, Issue 13, pp. 7715-27, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Flow Cytometry

Addison, Koontz, Fugett, Creighton, Chen, Farrugia, Padon, Voronkova, McLaughlin, Livengood, Lin, Ruppert, Pugacheva, Ivanov: "KAP1 promotes proliferation and metastatic progression of breast cancer cells." in: Cancer research, Vol. 75, Issue 2, pp. 344-55, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting

Jamin, Dehoux, Dossier, Fila, Heming, Monteiro, Deschênes: "Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome." in: Clinical and experimental immunology, Vol. 182, Issue 3, pp. 332-45, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Anagandula, Richardson, Oberste, Sioofy-Khojine, Hyöty, Morgan, Korsgren, Frisk et al.: "Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity ..." in: Journal of medical virology, Vol. 86, Issue 8, pp. 1402-11, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Hamidi, Schäfer-Korting, Weindl: "TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts." in: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 484-94, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Pohar, Pirher, Benčina, Manček-Keber, Jerala: "The ectodomain of TLR3 receptor is required for its plasma membrane translocation." in: PLoS ONE, Vol. 9, Issue 3, pp. e92391, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting

Tengroth, Millrud, Kvarnhammar, Kumlien Georén, Latif, Cardell: "Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e98239, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunohistochemistry (Paraffin-embedded Sections),Immunofluorescence

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