Caspase 8 Antikörper (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 449-464)

Details for Product anti-CASP8 Antibody No. ABIN4288161, Anbieter: Anmelden zum Anzeigen
Antigen
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8 L homeolog
  • death related ced-3/Nedd2-like protein
  • caspase 8
  • caspase-8
  • caspase-8-like
  • caspase 8, apoptosis-related cysteine peptidase
  • casp8.L
  • LOC661095
  • CASP8
  • LOC5563818
  • casp8
  • LOC100222284
  • Casp8
Epitop
AA 449-464, AA 464-479, AA 481-496, AA 523-538, C-Term
42
19
15
14
14
12
11
11
9
9
7
7
6
6
6
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
378
134
104
22
22
20
3
2
1
Wirt
Kaninchen
296
120
13
2
Klonalität
Polyklonal
Konjugat
Dieser Caspase 8 Antikörper ist unkonjugiert
22
16
9
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
394
134
111
76
51
40
38
35
19
14
13
8
8
5
2
2
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Synthetic peptide corresponding to the C-terminus of human Caspase-8 (PQPTFTLRKKLVFPSD). This sequence is common to various Caspase-8 forms including: 1. Caspase 8a (aa 481-496 GenBank no. NP_001219.2) 2. Caspase 8b (aa 464-479, GenBank no. NP_203519.1) 3. Caspase 8c (aa 449-464, GenBank no. NP_203520.1) 4. Caspase 8L (aa 523-538, GenBank no. gbAAL87628.1) 5. Truncated caspase 8 (as 251-266, GenBank no. gi3928274)
Spezifität Caspase-8
Reinigung Unpurified
Plasmids, Primers & others Plasmide, Primers & weitere Caspase 8 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung Caspase-8 (CASP8 Antibody Abstract)
Hintergrund Gene Symbol: CASP8
Gen-ID 841
NCBI Accession NP_001073595
Pathways Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Applikations-hinweise Western Blot 1:1000-1:2000, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin 1:1000-1:5000, Immunohistochemistry-FrozenNBP1-05123 has been successfully tested in immunoprecipitation, immunohistochemistry-Paraffin, immunohistochemistry-Frozen and Western blot applications.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Whole antisera
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (AA 449-464), (AA 464-479), (AA 481-496), (AA 523-538), (C-Term) antibody (ABIN4288161) Immunohistochemistry-Paraffin: Caspase-8 Antibody [NBP1-05123] - Formalin-fixed, para...
Produkt verwendet in: Tian, Clift, Casey, Del Pino, Pelaz, Conde, Byrne, Rothen-Rutishauser, Estrada, de la Fuente, Stoeger: "Investigating the role of shape on the biological impact of gold nanoparticles in vitro." in: Nanomedicine (London, England), Vol. 10, Issue 17, pp. 2643-57, 2015 (PubMed).

Liu, Zhao, Frissora, Ma, Santhanam, Jarjoura, Lehman, Perrotti, Chen, Dalton, Muthusamy, Byrd: "FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma." in: Blood, Vol. 111, Issue 1, pp. 275-84, 2007 (PubMed).

Svingen, Karp, Krajewski, Mesner, Gore, Burke, Reed, Lazebnik, Kaufmann: "Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia." in: Blood, Vol. 96, Issue 12, pp. 3922-31, 2000 (PubMed).

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