Anaphase Promoting Complex Subunit 11 (ANAPC11) (C-Term) Antikörper

Details zu Produkt Nr. ABIN4281020, Anbieter: Anmelden zum Anzeigen
Antigen
  • APC11
  • Apc11p
  • anapc11
  • RGD1561880
  • DDBDRAFT_0187183
  • DDBDRAFT_0231277
  • DDB_0187183
  • DDB_0231277
  • 1110011I19Rik
  • R75218
  • zgc:153671
  • si:dkey-237i9.4
  • anaphase promoting complex subunit 11
  • anaphase promoting complex subunit 11 L homeolog
  • anaphase-promoting complex subunit Apc11
  • ubiquitin-protein ligase Anaphase Promoting Complex
  • hypothetical protein
  • predicted protein
  • anaphase-promoting complex subunit 11
  • APC11 anaphase promoting complex subunit 11 homolog (yeast)
  • ANAPC11
  • anapc11.L
  • anapc11
  • Anapc11
  • APC11
  • apc11
  • CAALFM_CR10610CA
  • LOC9320604
  • LOC692923
Epitop
C-Term
22
7
6
4
3
3
2
1
1
1
1
1
Reaktivität
Human
118
29
27
16
3
1
Wirt
Kaninchen
66
43
11
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
107
63
27
18
13
13
8
7
3
2
2
1
Optionen
Hersteller
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Immunogen This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH.
Spezifität This product reacts with human and mouse APC11. Cross reactivity may also occur with APC11 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2.
Reinigung Sterile filtered
Antigen Anaphase Promoting Complex Subunit 11 (ANAPC11)
Andere Bezeichnung Apc11 (ANAPC11 Antibody Abstract)
Hintergrund Gene Symbol: ANAPC11
Gen-ID 51529
UniProt Q9NYG5
Applikations-hinweise Western Blot 1:500-1:1000, ELISA 1:2000-1:10000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates . Coimmunoprecipitation of related proteins does occur. A 9.8 kDa band corresponding - human APC11 is detected. Most cell lines or tissues expressing APC11 can be used as a positive control. Researchers should determine optimal titers for other applications.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer No buffer
Buffer contains: 0.01 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Produkt verwendet in: Furukawa, Ohta, Xiong: "Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15758-65, 2002 (PubMed).

Ohta, Michel, Xiong: "Association with cullin partners protects ROC proteins from proteasome-dependent degradation." in: Oncogene, Vol. 18, Issue 48, pp. 6758-66, 2000 (PubMed).

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