TLR8 Antikörper (Toll-Like Receptor 8) (Biotin)

Details for Product anti-TLR8 Antibody No. ABIN4248154, Anbieter: Anmelden zum Anzeigen
Antigen
  • CD288
  • toll like receptor 8
  • toll-like receptor 8
  • TLR8
  • Tlr8
Reaktivität
Human, Maus
237
115
48
1
1
1
1
1
1
1
Wirt
Maus
178
78
7
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser TLR8 Antikörper ist konjugiert mit Biotin
18
16
15
10
8
7
7
5
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA
167
119
82
71
44
15
14
13
8
4
4
4
3
3
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This antibody was developed against a KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850.
Klon 44C143
Isotyp IgG1 kappa
Reinigung Protein G purified
Plasmids, Primers & others Plasmide, Primers & weitere TLR8 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung TLR8 (TLR8 Antibody Abstract)
Hintergrund Gene Symbol: TLR8
Gen-ID 51311
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Applikations-hinweise ELISA 1:100-1:2000Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C. Do not freeze.
Produkt verwendet in: Chamberlain, Kim, Vila, Volin, Volkov, Pope, Arami, Mandelin, Shahrara: "Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNFα in monocytes." in: Annals of the rheumatic diseases, Vol. 72, Issue 3, pp. 418-26, 2013 (PubMed).

Abdi, Mutis, Garssen, Redegeld: "Characterization of the Toll-like receptor expression profile in human multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e60671, 2013 (PubMed).

Berger, Hsieh, Bakele, Marcos, Rieber, Kormann, Mays, Hofer, Neth, Vitkov, Krautgartner, von Schweinitz, Kappler, Hector, Weber, Hartl: "Neutrophils express distinct RNA receptors in a non-canonical way." in: The Journal of biological chemistry, Vol. 287, Issue 23, pp. 19409-17, 2012 (PubMed).

Harman, Bye, Nasr, Sandgren, Kim, Mercier, Botting, Lewin, Cunningham, Cameron: "Identification of lineage relationships and novel markers of blood and skin human dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 1, pp. 66-79, 2012 (PubMed).

Dasgupta, Chentoufi, You, Falatoonzadeh, Urbano, Akhtarmalik, Nguyen, Ablabutyan, Nesburn, BenMohamed: "Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses." in: Investigative ophthalmology & visual science, Vol. 52, Issue 6, pp. 3321-33, 2011 (PubMed).

Biasin, Piacentini, Lo Caputo, Naddeo, Pierotti, Borelli, Trabattoni, Mazzotta, Shearer, Clerici: "TLR activation pathways in HIV-1-exposed seronegative individuals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 5, pp. 2710-7, 2010 (PubMed). Weitere Details: Cell Sorting

Wu, Meng, Jiang, Zhang, Trippler, Broering, Bucchi, Krux, Dittmer, Yang, Roggendorf, Gerken, Lu, Schlaak: "Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific." in: Immunology, Vol. 129, Issue 3, pp. 363-74, 2010 (PubMed).

Clancy, Alvarez, Komissarova, Barrat, Swartz, Buyon: "Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 4, pp. 2148-55, 2010 (PubMed).

Panda, Qian, Mohanty, van Duin, Newman, Zhang, Chen, Towle, Belshe, Fikrig, Allore, Montgomery, Shaw: "Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 5, pp. 2518-27, 2010 (PubMed). Weitere Details: Flow Cytometry,Immunochromatography

van den Berk, Jansen, Siebers-Vermeulen, Netea, Latuhihin, Bergevoet, Raymakers, Kögler, Figdor, Adema, Torensma: "Toll-like receptor triggering in cord blood mesenchymal stem cells." in: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3415-26, 2010 (PubMed). (Probematerial (Species): Human).

Schwab, Zozulya, Kieseier, Toyka, Wiendl: "An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 9, pp. 5368-74, 2010 (PubMed). (Probematerial (Species): Human). Weitere Details: Cell Sorting,Flow Cytometry

Pietschmann, Beetz, Welte, Martens, Gruen, Oberg, Wesch, Kabelitz: "Toll-like receptor expression and function in subsets of human gammadelta T lymphocytes." in: Scandinavian journal of immunology, Vol. 70, Issue 3, pp. 245-55, 2009 (PubMed).

Kaji, Tanaka, Sugita, Kato, Ibata, Shono, Ohta, Kondo, Asaka, Imamura: "Ciprofloxacin inhibits lipopolysaccharide-induced toll-like receptor-4 and 8 expression on human monocytes derived from adult and cord blood." in: Annals of hematology, Vol. 87, Issue 3, pp. 229-31, 2008 (PubMed). (Probematerial (Species): Human).

Cohen, Koski, Czerniecki, Bunting, Fu, Wang, Zhang, Carter, Awad, Distel, Nagem, Paustian, Johnson, Tisdale, Shu: "STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells." in: Blood, Vol. 112, Issue 5, pp. 1832-43, 2008 (PubMed).

Clark, Huang, Murphy, Mollet, Hijnen, Muthukuru, Schanbacher, Edwards, Miller, Kim, Lambert, Kupper: "Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells." in: The Journal of experimental medicine, Vol. 205, Issue 10, pp. 2221-34, 2008 (PubMed).

Sacre, Lo, Gregory, Simmonds, Williams, Feldmann, Brennan, Foxwell: "Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 8002-9, 2008 (PubMed).

Zuiderwijk-Sick, van der Putten, Bsibsi, Deuzing, de Boer, Persoon-Deen, Kondova, Boven, van Noort, t Hart, Amor, Bajramovic: "Differentiation of primary adult microglia alters their response to TLR8-mediated activation but not their capacity as APC." in: Glia, Vol. 55, Issue 15, pp. 1589-600, 2007 (PubMed). (Probematerial (Species): Human).

Zola, Swart, Banham, Barry, Beare, Bensussan, Boumsell, D Buckley, Bühring, Clark, Engel, Fox, Jin, Macardle, Malavasi, Mason, Stockinger, Yang: "CD molecules 2006--human cell differentiation molecules." in: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 1-5, 2007 (PubMed).

Wong, Cheung, Ip, Lam: "Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils." in: American journal of respiratory cell and molecular biology, Vol. 37, Issue 1, pp. 85-96, 2007 (PubMed).

Murciano, Villamón, Yáñez, Murciano, Mir, OConnor, Gozalbo, Gil: "In vitro response to Candida albicans in cultures of whole human blood from young and aged donors." in: FEMS immunology and medical microbiology, Vol. 51, Issue 2, pp. 327-35, 2007 (PubMed).

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