Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MARK2 Antikörper (Isoform A, pThr595)

MARK2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401318
  • Target Alle MARK2 Antikörper anzeigen
    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
    Bindungsspezifität
    • 13
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform A, pThr595
    Reaktivität
    • 74
    • 49
    • 40
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund
    Wirt
    • 70
    • 3
    • 1
    Kaninchen
    Klonalität
    • 62
    • 12
    Polyklonal
    Konjugat
    • 37
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MARK2 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 37
    • 22
    • 16
    • 11
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is directed against the phosphorylated form of MARK2 at thepT595 residue.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Canine, Bovine, Mouse, Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Synthetic peptide corresponding to amino acids surrounding T595 of Human MARK2 isoform a. The immunogen peptide was phosphorylated at the residue corresponding to T595
    Isotyp
    IgG
    Top Product
    Discover our top product MARK2 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000 - 1/3,000. Western Blot: 1/250 - 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.6 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
  • Target
    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
    Andere Bezeichnung
    MARK2 (MARK2 Produkte)
    Synonyme
    EMK-1 antikoerper, EMK1 antikoerper, PAR-1 antikoerper, Par-1b antikoerper, Par1b antikoerper, AU024026 antikoerper, Emk antikoerper, Par-1 antikoerper, mKIAA4207 antikoerper, microtubule affinity regulating kinase 2 antikoerper, MAP/microtubule affinity regulating kinase 2 antikoerper, MARK2 antikoerper, Mark2 antikoerper
    Hintergrund
    This antibody recognizes a regulatory phosphorylation on a kinase that is critical to regulation of microtubules, cell cycle and immune responses. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encode two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gives rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be co-expressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA that is ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.Synonyms: 2, ELKL motif kinase, EMK1, MAP/microtubule affinity-regulating kinase, MARK2, PAR1 homolog, Serine/threonine-protein kinase
    Gen-ID
    2011
    NCBI Accession
    NP_001034558
    UniProt
    Q7KZI7
    Pathways
    SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Sie sind hier:
Kundenservice