Interleukin 1 Family Member 9 (IL1F9) (AA 1-111) Antikörper

Details zu Produkt Nr. ABIN396796, Anbieter: Anmelden zum Anzeigen
Antigen
  • IL-1F9
  • IL-1H1
  • IL-1RP2
  • IL1E
  • IL1F9
  • IL1H1
  • IL1RP2
  • Il36g
  • Il1f9
  • RGD1563019
  • IL36G
  • interleukin 36 gamma
  • interleukin 1 family, member 9
  • interleukin 36, gamma
  • interleukin-36 gamma
  • IL36G
  • Il1f9
  • Il36g
  • LOC100065031
Epitop
AA 1-111
9
6
5
3
3
3
2
2
2
2
2
1
1
Reaktivität
Human
61
19
3
1
1
Wirt
Maus
50
16
14
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
6
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
73
34
25
10
9
8
7
7
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen

Antigen Type: Recombinant Protein

Target/Specificity: IL1F9 (NP_062564, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon 8A11
Isotyp IgG1 kappa
Spezifität IL1F9 (NP_062564, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Kreuzreaktivität (Details) Human: ~~ Positive
Reinigung This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Antigen
Andere Bezeichnung IL1F9 (IL1F9 Antibody Abstract)
Hintergrund

Other Names: Interleukin-36 gamma, IL-1-related protein 2, IL-1RP2, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 9, IL-1F9, Interleukin-1 homolog 1, IL-1H1, IL36G, IL1E, IL1F9, IL1H1, IL1RP2

Gene Description: interleukin 1 family, member 9

Gene Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq

Molekulargewicht 18721 DA
Gen-ID 56300
NCBI Accession NP_062564, NP_001265497
UniProt Q9NZH8
Applikations-hinweise ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Kommentare

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer Clear, colorless solution in phosphate buffered saline,  pH 7.2 .
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Interleukin 1 Family Member 9 (IL1F9) (AA 1-111) antibody (ABIN396796) Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunoge...
ELISA image for anti-Interleukin 1 Family Member 9 (IL1F9) (AA 1-111) antibody (ABIN396796) Detection limit for recombinant GST tagged IL1F9 is approximately 0.03ng/ml as a capt...
Allgemeine Veröffentlichungen Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Jung, Kang, Kim, Kim, Yun, Yim, Hong, Chung: "The interleukin-1 family gene polymorphisms in Korean patients with rheumatoid arthritis." in: Scandinavian journal of rheumatology, Vol. 39, Issue 3, pp. 190-6, 2010 (PubMed).

Kim, Kim, Lee, Peddle, Rahman, Hu, Greenwood, Inman: "Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea." in: The Journal of rheumatology, Vol. 35, Issue 8, pp. 1603-8, 2008 (PubMed).

Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Vos, van Sterkenburg, Rabe, Schalkwijk, Hiemstra, Datson: "Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense." in: Physiological genomics, Vol. 21, Issue 3, pp. 324-36, 2005 (PubMed).

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