PTP4A3 Antikörper

Produktnummer ABIN392854

Produktdetails anti-PTP4A3 Antikörper

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTP4A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PRL3 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL3.

Klon: RB7265

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PTP4A3

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Andere Bezeichnung: PRL3 (PTP4A3 Produkte)

Synonyme: PRL-3 antikoerper, PRL-R antikoerper, PRL3 antikoerper, wu:fc54b05 antikoerper, wu:fv52d11 antikoerper, zgc:77109 antikoerper, prl-3 antikoerper, prl3 antikoerper, ptpcaax3 antikoerper, PTP4A3 antikoerper, AV088979 antikoerper, Prl-3 antikoerper, pPtp4a3 antikoerper, protein tyrosine phosphatase type IVA, member 3 antikoerper, protein tyrosine phosphatase type IVA, member 3 L homeolog antikoerper, protein tyrosine phosphatase 4a3 antikoerper, PTP4A3 antikoerper, ptp4a3 antikoerper, ptp4a3.L antikoerper, Ptp4a3 antikoerper

Hintergrund: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.

Molekulargewicht: 19535

Gen-ID: 11156

NCBI Accession: NP_009010, NP_116000

UniProt: O75365