NPR1 Antikörper (N-Term)

Produktnummer ABIN392702

Produktdetails anti-NPR1 Antikörper

Target: NPR1 (Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Natriuretic Peptide Receptor A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Natriuretic Peptide Receptor A.

Klon: RB03496

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-NPR1 Antikörper (ABIN392702)

Abdelalim, Masuda, Tooyama: "Expression of natriuretic peptide-activated guanylate cyclases by cholinergic and dopaminergic amacrine cells of the rat retina." in: Peptides, Vol. 29, Issue 4, pp. 622-8, (2008) (PubMed).

Dams, Van Acker, Gustin, Vereycken, Bunkens, Holemans, Smeulders, Clayton, Ohagen, Hertogs: "A time-resolved fluorescence assay to identify small-molecule inhibitors of HIV-1 fusion." in: Journal of biomolecular screening, Vol. 12, Issue 6, pp. 865-74, (2007) (PubMed).

Tomescot, Leschik, Bellamy, Dubois, Messas, Bruneval, Desnos, Hagège, Amit, Itskovitz, Menasché, Pucéat: "Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 9, pp. 2200-5, (2007) (PubMed).

Details zu NPR1

Target: NPR1 (Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1))

Andere Bezeichnung: Natriuretic Peptide Receptor A (NPR1/ANPA) (NPR1 Produkte)

Synonyme: ANPRA antikoerper, ANPa antikoerper, GUC2A antikoerper, GUCY2A antikoerper, NPRA antikoerper, Anpra antikoerper, Gca antikoerper, NPR-A antikoerper, Npra antikoerper, sGC antikoerper, si:dkey-27c15.1 antikoerper, AI893888 antikoerper, GC-A antikoerper, Pndr antikoerper, ARABIDOPSIS NONEXPRESSER OF PR GENES 1 antikoerper, ATNPR1 antikoerper, F15H21.6 antikoerper, F15H21_6 antikoerper, NIM1 antikoerper, NON-INDUCIBLE IMMUNITY 1 antikoerper, NONEXPRESSER OF PR GENES 1 antikoerper, REGULATORY PROTEIN NPR1 antikoerper, SAI1 antikoerper, SALICYLIC ACID INSENSITIVE 1 antikoerper, natriuretic peptide receptor 1 antikoerper, natriuretic peptide receptor 1a antikoerper, regulatory protein (NPR1) antikoerper, NPR1 antikoerper, Npr1 antikoerper, npr1a antikoerper

Hintergrund: ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.

Molekulargewicht: 118919

Gen-ID: 4881

NCBI Accession: NP_000897

UniProt: P16066