PACSIN1 Antikörper (AA 8-38)

Produktnummer ABIN392665

Produktdetails anti-PACSIN1 Antikörper

Target: PACSIN1 (Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1))

Bindungsspezifität: AA 8-38

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACSIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M, Rat, C, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PACSIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-38 amino acids from the Central region of human PACSIN1.

Klon: RB3587

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PACSIN1

Target: PACSIN1 (Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1))

Andere Bezeichnung: PACSIN1 (PACSIN1 Produkte)

Synonyme: MGC84055 antikoerper, sdpii antikoerper, pacsin1 antikoerper, x-PACSIN2 antikoerper, fe25d06 antikoerper, wu:fe25d06 antikoerper, zgc:114042 antikoerper, PACSIN1 antikoerper, SDPI antikoerper, A830061D09Rik antikoerper, H74 antikoerper, mKIAA1379 antikoerper, syndapin antikoerper, protein kinase C and casein kinase substrate in neurons 1 antikoerper, protein kinase C and casein kinase substrate in neurons 1 S homeolog antikoerper, protein kinase C and casein kinase substrate in neurons 2 antikoerper, protein kinase C and casein kinase substrate in neurons 1b antikoerper, PACSIN1 antikoerper, pacsin1.S antikoerper, pacsin2 antikoerper, pacsin1b antikoerper, Pacsin1 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Molekulargewicht: 50966

Gen-ID: 29993

NCBI Accession: NP_001186512, NP_065855

UniProt: Q9BY11