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TRPM6 Antikörper (AA 317-348)

TRPM6 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3407 unconjugated
Produktnummer ABIN392616
  • Target Alle TRPM6 Antikörper anzeigen
    TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
    Bindungsspezifität
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 317-348
    Reaktivität
    • 23
    • 17
    • 17
    Human
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRPM6 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 9
    • 8
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).
    Klon
    RB3407
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Furukawa, Fujii, Manabe, Matsunaga, Endo, Hasegawa, Ito, Yamaguchi, Yamazaki, Ikari: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).

    Ikari, Okude, Sawada, Takahashi, Sugatani, Miwa: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).

    Ikari, Okude, Sawada, Yamazaki, Sugatani, Miwa: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).

  • Target
    TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
    Andere Bezeichnung
    TRPM6 (CHAK2) (TRPM6 Produkte)
    Synonyme
    TRPM6 antikoerper, CHAK2 antikoerper, HMGX antikoerper, HOMG antikoerper, HOMG1 antikoerper, HSH antikoerper, TRPM6/CHAK2 antikoerper, transient receptor potential cation channel subfamily M member 6 antikoerper, transient receptor potential cation channel, subfamily M, member 6 antikoerper, TRPM6 antikoerper, Trpm6 antikoerper
    Hintergrund
    CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.
    Molekulargewicht
    231708
    Gen-ID
    140803
    NCBI Accession
    NP_001170781, NP_001170782, NP_060132
    UniProt
    Q9BX84
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