MAP3K14 Antikörper (AA 119-148)

Produktnummer ABIN392496

Produktdetails anti-MAP3K14 Antikörper

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Bindungsspezifität: AA 119-148

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK.

Klon: RB3337

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Andere Bezeichnung: NIK (MAP3K14 Produkte)

Synonyme: FTDCR1B antikoerper, HS antikoerper, HSNIK antikoerper, NIK antikoerper, F23F1.4 antikoerper, F23F1_4 antikoerper, mitogen-activated protein kinase kinase kinase 14 antikoerper, Nik antikoerper, aly antikoerper, mitogen-activated protein kinase kinase kinase 14 antikoerper, MAP3K14 antikoerper, Map3k14 antikoerper, MAPKKK14 antikoerper

Hintergrund: NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Molekulargewicht: 104042

Gen-ID: 9020

NCBI Accession: NP_003945

UniProt: Q99558

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg