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PDGFRA Antikörper (AA 698-727)

PDGFRA Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB11101 unconjugated
Produktnummer ABIN392024
  • Target Alle PDGFRA Antikörper anzeigen
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Bindungsspezifität
    • 23
    • 16
    • 16
    • 15
    • 15
    • 15
    • 11
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 698-727
    Reaktivität
    • 248
    • 130
    • 71
    • 19
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 221
    • 41
    • 9
    • 1
    Kaninchen
    Klonalität
    • 213
    • 59
    Polyklonal
    Konjugat
    • 116
    • 22
    • 19
    • 16
    • 15
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    Dieser PDGFRA Antikörper ist unkonjugiert
    Applikation
    • 180
    • 114
    • 72
    • 54
    • 54
    • 47
    • 37
    • 24
    • 24
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    C, Rat, X
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from human PDGFRA.
    Klon
    RB11101
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PDGFRA Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Guan, Wei, Wu, Fang, Liao, Xiao, Li, Li: "Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 8, pp. E1334-44, (2013) (PubMed).

  • Target
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Andere Bezeichnung
    PDGFRA (PDGFRA Produkte)
    Synonyme
    AI115593 antikoerper, CD140a antikoerper, Pdgfr-2 antikoerper, APDGFR antikoerper, PDGFACE antikoerper, CD140A antikoerper, PDGFR-2 antikoerper, PDGFR2 antikoerper, RHEPDGFRA antikoerper, PDGFR antikoerper, PDGFR-A antikoerper, platelet derived growth factor receptor alpha antikoerper, platelet derived growth factor receptor, alpha polypeptide antikoerper, platelet-derived growth factor receptor, alpha polypeptide L homeolog antikoerper, platelet-derived growth factor receptor, alpha polypeptide antikoerper, PDGFRA antikoerper, Pdgfra antikoerper, pdgfra.L antikoerper
    Hintergrund
    PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
    Molekulargewicht
    122670
    Gen-ID
    5156
    NCBI Accession
    NP_006197
    UniProt
    P16234
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling
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