PANK2 Antikörper (AA 180-210)
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- Target Alle PANK2 Antikörper anzeigen
- PANK2 (Pantothenate Kinase 2 (PANK2))
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Bindungsspezifität
- AA 180-210
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PANK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human PANK2.
- Klon
- RB5487
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PANK2 Primärantikörper
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anti-Pantothenate Kinase 2 (PANK2) antibody
PANK2 Reaktivität: Human, Ratte, Hund, Affe WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 3H9 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 437-490) antibodyPANK2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 205-260) antibodyPANK2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2B12 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 65-95) antibodyPANK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 65-95), (N-Term) antibodyPANK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB5486 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (N-Term) antibodyPANK2 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 300-400) antibodyPANK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 459-508) antibodyPANK2 Reaktivität: Human, Ratte, Hund, Rind (Kuh), Pferd, Schaf, Schwein, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) antibodyPANK2 Reaktivität: Human WB, IF, FACS Wirt: Maus Monoclonal 3G4 unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- PANK2 (Pantothenate Kinase 2 (PANK2))
- Andere Bezeichnung
- PANK2 (PANK2 Produkte)
- Hintergrund
- Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).
- Molekulargewicht
- 62681
- Gen-ID
- 80025
- NCBI Accession
- NP_079236, NP_705902, NP_705904
- UniProt
- Q9BZ23
- Pathways
- Ribonucleoside Biosynthetic Process
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