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PRKAG3 Antikörper (AA 148-178)

PRKAG3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB3191 unconjugated
Produktnummer ABIN391060
  • Target Alle PRKAG3 Antikörper anzeigen
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 148-178
    Reaktivität
    • 62
    • 11
    • 1
    Human, Maus
    Wirt
    • 54
    • 9
    • 1
    Kaninchen
    Klonalität
    • 55
    • 9
    Polyklonal
    Konjugat
    • 23
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRKAG3 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 33
    • 15
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-178 amino acids from the Central region of human PRKAG3.
    Klon
    RB3191
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PRKAG3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Okoshi, Ohta, Ishikawa, Sato, Kizaki: "Expression of 5'-AMP-activated protein kinase with starvation in murine thymocytes." in: The Bulletin of Tokyo Dental College, Vol. 52, Issue 1, pp. 21-9, (2011) (PubMed).

    Fukuyama, Ohta, Okoshi, Suehara, Kizaki, Nakagawa: "Hypoxia induces expression and activation of AMPK in rat dental pulp cells." in: Journal of dental research, Vol. 86, Issue 9, pp. 903-7, (2007) (PubMed).

  • Target
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    Andere Bezeichnung
    PRKAG3 (PRKAG3 Produkte)
    Synonyme
    Ampkg3 antikoerper, prkag3-a antikoerper, PRKAG3 antikoerper, AMPKG3 antikoerper, AMPKg3L antikoerper, AMPKg3S antikoerper, Amkg3 antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 3 antikoerper, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antikoerper, Prkag3 antikoerper, PRKAG3 antikoerper, prkag3.S antikoerper, prkag3-b antikoerper
    Hintergrund
    PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
    Molekulargewicht
    54258
    Gen-ID
    53632
    NCBI Accession
    NP_059127
    UniProt
    Q9UGI9
    Pathways
    AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effekt
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