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GRB2 Antikörper (AA 187-216)
GRB2
Reaktivität: Human
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
RB11305-11306
unconjugated
Produktdetails anti-GRB2 Antikörper
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Target
Alle GRB2 Antikörper anzeigen
GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Bindungsspezifität
Alle Epitope für GRB2 Antikörper
AA 187-216
Reaktivität
Alle Reaktivitäten für GRB2 Antikörper
Human
Wirt
Alle Wirte für GRB2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GRB2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GRB2 Antikörper
Dieser GRB2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GRB2 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
X, C, M, Rat
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
Klon
RB11305-11306
Isotyp
Ig Fraction
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Discover our top product GRB2 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
WB: 1:1000. IHC-P: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Referenzen für anti-GRB2 Antikörper (ABIN390236)
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Gogate, Kurenova, Ethirajan, Liao, Yemma, Sen, Pandey, Cance : "Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer. " in: Cancer letters , Vol. 353 , Issue 2 , pp. 281-9 , (2014 ) (PubMed ).
Details zu GRB2
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Target
GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Andere Bezeichnung
GRB2 (GRB2 Produkte )
Synonyme
GRB2 antikoerper, grb2 antikoerper, AA408164 antikoerper, Ash antikoerper, ASH antikoerper, EGFRBP-GRB2 antikoerper, Grb3-3 antikoerper, MST084 antikoerper, MSTP084 antikoerper, NCKAP2 antikoerper, wu:fb18e12 antikoerper, wu:fb34e06 antikoerper, zgc:73077 antikoerper, growth factor receptor bound protein 2 antikoerper, growth factor receptor-bound protein 2 antikoerper, growth factor receptor-bound protein 2b antikoerper, GRB2 antikoerper, grb2 antikoerper, Grb2 antikoerper, grb2b antikoerper
Hintergrund
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
Molekulargewicht
25206
Gen-ID
2885
NCBI Accession
NP_002077 , NP_987102
UniProt
P62993
Pathways
RTK Signalweg , T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Regulation of Actin Filament Polymerization , Hepatitis C , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , EGFR Downregulation
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