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GRB2 Antikörper (AA 187-216)

GRB2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB11305-11306 unconjugated
Produktnummer ABIN390236
  • Target Alle GRB2 Antikörper anzeigen
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-216
    Reaktivität
    • 65
    • 33
    • 32
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 51
    • 11
    • 3
    Kaninchen
    Klonalität
    • 52
    • 12
    • 1
    Polyklonal
    Konjugat
    • 46
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GRB2 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 33
    • 20
    • 11
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    X, C, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
    Klon
    RB11305-11306
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GRB2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Gogate, Kurenova, Ethirajan, Liao, Yemma, Sen, Pandey, Cance: "Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer." in: Cancer letters, Vol. 353, Issue 2, pp. 281-9, (2014) (PubMed).

  • Target
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    Andere Bezeichnung
    GRB2 (GRB2 Produkte)
    Synonyme
    GRB2 antikoerper, grb2 antikoerper, AA408164 antikoerper, Ash antikoerper, ASH antikoerper, EGFRBP-GRB2 antikoerper, Grb3-3 antikoerper, MST084 antikoerper, MSTP084 antikoerper, NCKAP2 antikoerper, wu:fb18e12 antikoerper, wu:fb34e06 antikoerper, zgc:73077 antikoerper, growth factor receptor bound protein 2 antikoerper, growth factor receptor-bound protein 2 antikoerper, growth factor receptor-bound protein 2b antikoerper, GRB2 antikoerper, grb2 antikoerper, Grb2 antikoerper, grb2b antikoerper
    Hintergrund
    GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
    Molekulargewicht
    25206
    Gen-ID
    2885
    NCBI Accession
    NP_002077, NP_987102
    UniProt
    P62993
    Pathways
    RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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