MMP24 Antikörper (AA 396-425)

Produktnummer ABIN390145

Produktdetails anti-MMP24 Antikörper

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Bindungsspezifität: AA 396-425

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MMP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the Central region of human MMP24.

Klon: RB2041-2042

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MMP24

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Andere Bezeichnung: MMP24 (MMP24 Produkte)

Synonyme: MMP-24 antikoerper, MMP25 antikoerper, MT-MMP 5 antikoerper, MT-MMP5 antikoerper, MT5-MMP antikoerper, MT5MMP antikoerper, MTMMP5 antikoerper, AU040325 antikoerper, Mt5-mmp antikoerper, si:ch211-239j9.5 antikoerper, MMP24 antikoerper, mt3-mmp antikoerper, matrix metallopeptidase 24 antikoerper, matrix metallopeptidase 16 S homeolog antikoerper, MMP24 antikoerper, Mmp24 antikoerper, mmp24 antikoerper, mmp16.S antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP24 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed matrix metalloproteinase 24 (MMP24).

Molekulargewicht: 73231

Gen-ID: 10893

NCBI Accession: NP_006681

UniProt: Q9Y5R2