UVRAG Antikörper (AA 366-398)

Produktnummer ABIN388587

Produktdetails anti-UVRAG Antikörper

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Bindungsspezifität: AA 366-398

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UVRAG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-398 amino acids from the Central region of human UVRAG.

Klon: RB10847

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu UVRAG

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Andere Bezeichnung: UVRAG (UVRAG Produkte)

Synonyme: DHTX antikoerper, VPS38 antikoerper, p63 antikoerper, 9530039D02Rik antikoerper, AI648770 antikoerper, BB124205 antikoerper, Uvrag1 antikoerper, Uvragl antikoerper, zgc:56164 antikoerper, uvrag antikoerper, MGC81810 antikoerper, UVRAG antikoerper, MGC131135 antikoerper, CG6116 antikoerper, Dmel\\CG6116 antikoerper, UV radiation resistance associated antikoerper, UV radiation resistance associated gene antikoerper, UV radiation resistance associated S homeolog antikoerper, UV radiation resistance associated L homeolog antikoerper, UV-resistance associated gene antikoerper, UVRAG antikoerper, Uvrag antikoerper, uvrag antikoerper, uvrag.S antikoerper, uvrag.L antikoerper

Hintergrund: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Molekulargewicht: 78151

Gen-ID: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5