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PUMA Antikörper (AA 119-154)

BBC3 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01353 unconjugated
Produktnummer ABIN388112
  • Target Alle PUMA (BBC3) Antikörper anzeigen
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Bindungsspezifität
    • 21
    • 18
    • 16
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 119-154
    Reaktivität
    • 113
    • 40
    • 39
    • 16
    Human
    Wirt
    • 109
    • 7
    • 1
    Kaninchen
    Klonalität
    • 98
    • 19
    Polyklonal
    Konjugat
    • 52
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PUMA Antikörper ist unkonjugiert
    Applikation
    • 98
    • 40
    • 39
    • 22
    • 21
    • 16
    • 16
    • 14
    • 13
    • 9
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.
    Klon
    RB01353
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product BBC3 Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Vesela, Matalova: "Detection of Bim and Puma in mouse hair follicles using immunofluorescence and TUNEL assay double staining." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, pp. 1-7, (2015) (PubMed).

  • Target
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Andere Bezeichnung
    Puma (BBC3 Produkte)
    Synonyme
    BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
    Hintergrund
    PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
    Molekulargewicht
    20532
    Gen-ID
    27113
    NCBI Accession
    NP_001120712, NP_001120713, NP_001120714, NP_055232
    UniProt
    Q9BXH1
    Pathways
    p53 Signalweg, Positive Regulation of Endopeptidase Activity
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