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SLC29A1 Antikörper (AA 234-263)

SLC29A1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB28016 unconjugated
Produktnummer ABIN387941
  • Target Alle SLC29A1 Antikörper anzeigen
    SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 234-263
    Reaktivität
    • 86
    • 21
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 86
    • 2
    • 1
    Kaninchen
    Klonalität
    • 88
    Polyklonal
    Konjugat
    • 38
    • 9
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLC29A1 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 45
    • 19
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the Central region of rat ENT1(O54698).
    Klon
    RB28016
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:2000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Haltbarkeit
    6 months
  • Niemann, Haufs-Brusberg, Puetz, Feickert, Jaeckstein, Hoffmann, Zurkovic, Heine, Trautmann, Müller, Tönjes, Schlein, Jafari, Eltzschig, Gnad, Blüher, Krahmer, Kovacs, Heeren, Pfeifer: "Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine." in: Nature, (2022) (PubMed).

    Ibarra, Pfeiffer: "Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance." in: Journal of virology, Vol. 83, Issue 9, pp. 4538-47, (2009) (PubMed).

  • Target
    SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))
    Andere Bezeichnung
    ENT1 (SLC29A1 Produkte)
    Synonyme
    ENT1 antikoerper, rENT1 antikoerper, 1200014D21Rik antikoerper, AA407560 antikoerper, solute carrier family 29 member 1 (Augustine blood group) antikoerper, solute carrier family 29 member 1 antikoerper, solute carrier family 29 (nucleoside transporters), member 1 antikoerper, SLC29A1 antikoerper, Slc29a1 antikoerper
    Hintergrund
    ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
    Molekulargewicht
    50219
    Gen-ID
    2030
    NCBI Accession
    NP_001071642, NP_001071643, NP_001071644, NP_001071645, NP_004946
    UniProt
    Q99808
    Pathways
    Carbohydrate Homeostasis, Synaptic Membrane
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