VPS39 Antikörper

Produktnummer ABIN375361

Produktdetails anti-VPS39 Antikörper

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS39 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Reacts with human VPS39 102 kDa protein

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Cross reacts with mouse and other species.

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from an internal domain of human Vam6 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/500 to 1/2 000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu VPS39

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Andere Bezeichnung: Vam6/Vps39-Like Protein (VPS39) (VPS39 Produkte)

Synonyme: lbk antikoerper, vam6 antikoerper, DKFZp469J2314 antikoerper, A230065P22Rik antikoerper, AW743070 antikoerper, Vam6 antikoerper, Vam6P antikoerper, mVam6 antikoerper, TLP antikoerper, VAM6 antikoerper, hVam6p antikoerper, VPS39, HOPS complex subunit antikoerper, vacuolar protein sorting 39 homolog (S. cerevisiae) antikoerper, vam6/Vps39-like protein antikoerper, vacuolar protein sorting 39 antikoerper, VPS39 HOPS complex subunit antikoerper, VPS39 antikoerper, vps39 antikoerper, LOC100196283 antikoerper, NAEGRDRAFT_59276 antikoerper, Vps39 antikoerper

Hintergrund: May play a role in clustering and fusion of late endosomes and lysosomes. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription.

UniProt: Q96JC1

Pathways: SARS-CoV-2 Protein Interaktom