Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Granulin Antikörper (Internal Region)

GRN Reaktivität: Human WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN375134
  • Target Alle Granulin (GRN) Antikörper anzeigen
    Granulin (GRN)
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 51
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 9
    • 5
    • 2
    • 1
    Ziege
    Klonalität
    • 48
    • 11
    Polyklonal
    Konjugat
    • 35
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Granulin Antikörper ist unkonjugiert
    Applikation
    • 52
    • 19
    • 17
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    Western Blotting (WB)
    Spezifität
    This antibody recognizes Granulin / GRN.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography
    Immunogen
    Peptide with sequence QSKCLSKENATTD, from the internal region of the protein sequence according to NP_002078.1.
    Top Product
    Discover our top product GRN Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Granulin (GRN)
    Andere Bezeichnung
    Granulins (GRN) (GRN Produkte)
    Synonyme
    GRN antikoerper, grn antikoerper, wu:fb11g12 antikoerper, wu:fj18f05 antikoerper, MGC53354 antikoerper, DKFZp459H066 antikoerper, CLN11 antikoerper, GEP antikoerper, GP88 antikoerper, PCDGF antikoerper, PEPI antikoerper, PGRN antikoerper, epithelin antikoerper, acrogranin antikoerper, granulin precursor antikoerper, granulin a antikoerper, Granulins antikoerper, granulin L homeolog antikoerper, granulin antikoerper, GRN antikoerper, grna antikoerper, grn antikoerper, grn.L antikoerper, granulin antikoerper, ORF1 granulin antikoerper, Grn antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth. Tissue specificity: In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney. Involvement in disease: Defects in GRN are the cause of ubiquitin-positive frontotemporal dementia (UP-FTD) [MIM:607485], also known as tau-negative frontotemporal dementia linked to chromosome 17. Frontotemporal dementia (FTD) is the second most common cause of dementia in people under the age of 65 years. It is an autosomal dominant neurodegenerative disease.Synonyms: GRN, Granulins, PEPI, Proepithelin
    Molekulargewicht
    63.5 kDa (NP_002078.1)
    Gen-ID
    2896, 9606
    UniProt
    P28799
Sie sind hier:
Kundenservice