SLC40A1 Antikörper (N-Term)

Produktnummer ABIN372307

Produktdetails anti-SLC40A1 Antikörper

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC40A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes MTP1/SLC40A1 (N-term).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to N-terminal residues of Human MTP1 (Metal Transporter Protein 1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Andere Bezeichnung: MTP1 (SLC40A1 Produkte)

Synonyme: FPN1 antikoerper, HFE4 antikoerper, IREG1 antikoerper, MST079 antikoerper, MTP1 antikoerper, SLC11A3 antikoerper, slc39a1 antikoerper, weh antikoerper, slc40a1 antikoerper, MGC82700 antikoerper, SLC40A1 antikoerper, Fpn1 antikoerper, Slc11a3 antikoerper, Slc39a1 antikoerper, Dusg antikoerper, MTP antikoerper, Ol5 antikoerper, Pcm antikoerper, ARABIDOPSIS THALIANA IRON-REGULATED PROTEIN 1 antikoerper, ATIREG1 antikoerper, FERROPORTIN 1 antikoerper, T19C21.5 antikoerper, T19C21_5 antikoerper, iron regulated 1 antikoerper, ARABIDOPSIS IRON-REGULATED TRANSPORTER 1 antikoerper, ATIRT1 antikoerper, T16H5.50 antikoerper, T16H5_50 antikoerper, iron-regulated transporter 1 antikoerper, solute carrier family 40 member 1 antikoerper, solute carrier family 40 (iron-regulated transporter), member 1 antikoerper, solute carrier family 40 (iron-regulated transporter), member 1 S homeolog antikoerper, iron regulated 1 antikoerper, iron-regulated transporter 1 antikoerper, SLC40A1 antikoerper, slc40a1 antikoerper, slc40a1.S antikoerper, Slc40a1 antikoerper, IREG1 antikoerper, IRT1 antikoerper

Hintergrund: SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.Synonyms: Ferroportin-1, Fpn1, Ireg1, Iron-regulated transporter 1, Metal transporter protein 1, Slc11a3, Slc39a1, Slc40a1, Solute carrier family 40 member 1

Molekulargewicht: 63 kDa

Gen-ID: 30061

NCBI Accession: NP_055400

UniProt: Q9NP59

Pathways: Transition Metal Ion Homeostasis